Robert Chen, MA, MBBChir, MSc, FRCPC
Toronto Western Hospital, University Health Network
7MC409, 399 Bathurst Street
Toronto, ON
Canada M5T 2S8
Telephone: (416) 603 5207, (416) 603 5424
Email: robert.chen@uhn.ca
Date of Preparation: January 8, 2020
ACADEMIC APPOINTMENTS
2008-present Professor, Division of Neurology, Department of Medicine, University of Toronto
2006-present Catherine Manson Chair in Movement Disorders, University Health Network
2004-present Senior Scientist, Krembil Research Institute (formerly Toronto Western Research Institute)
1998-present Attending Neurologist, University Health Network
1998-present Member, Institute of Medical Sciences, University of Toronto
2003-2008 Associate Professor, Division of Neurology, Department of Medicine, Faculty of Medicine, University of Toronto
1998-2004 Scientist, Toronto Western Research Institute
1998-2003 Assistant Professor, Division of Neurology, Department of Medicine, University of Toronto
POSTGRADUATE TRAINING
1995-1998 Senior Staff Fellow, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, U.S.A.
1992-1995 Resident in Neurology, University of Western Ontario, London, Ontario, Canada.
1991-1992 Resident in Internal Medicine, Queen’s University, Kingston, Ontario, Canada.
1990-1991 Research Fellow, Division of Neurology and Playfair Neuroscience Unit, University of Toronto, Ontario, Canada.
1990 House Physician, Guy’s Hospital, London, United Kingdom.
1989-1990 House Surgeon, Lewisham Hospital, London, United Kingdom.
EDUCATION
1992 Masters of Science, University of Toronto
1990 Master of Arts, University of Cambridge, United Kingdom
1989 Bachelor of Surgery, University of Cambridge, United Kingdom
1989 Bachelor of Medicine, University of Cambridge, United Kingdom
1986 Bachelor of Arts, University of Cambridge, United Kingdom
AWARDS AND DISTINCTIONS
2003 Allan Bruce Robertson Young Investigator Award, Clinical Research Society of Toronto
2000 Doctor of Excellence Award, Dystonia Medical Research Foundation
1998 Herbert Jasper Prize, Canadian Society of Clinical Neurophysiologists
1996 Francis McNaughton Memorial Prize for Clinical Research, Canadian Neurological Society
1995 Miles Prize in Neurocritical Care, Canadian Neurocritical Care Group
1995 First Prize at annual residents’ and fellows’ research day, Department of Clinical Neurological Science, University of Western Ontario
1989 Treasurer’s Medal and Prize and Baldwin Prize in Clinical Medicine, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, University of London (UMDS)
1989 Gilbert Prize in Rheumatology, UMDS
1988 Charles Symonds Prize in Neurology, UMDS
1988 Beaney Prize in Immunology, UMDS
1988 Golding Bird Prize in Bacteriology, UMDS
1988 Ophthalmology Firm Prize, UMDS
1985 Senior Scholarship, King’s College, University of Cambridge
1985 Glynn Prize, King’s College, University of Cambridge
1984 Barcroft Prize, King’s College, University of Cambridge
1983-5 Entrance Scholarship, King’s College, University of Cambridge
1983 Old Boys’ Association Gold Medal Award, St. Joseph`s College, Hong Kong
1982 Belilos Scholarship, St. Joseph`s College, Hong Kong
1981 Best All-round student, St. Joseph`s College, Hong Kong
1981 Bro. Gilbert Scholarship, St. Joseph`s College, Hong Kong
PEER-REVIEWED RESEARCH GRANTS
(Unless otherwise stated, amount is in Canadian dollars)
Medical Research Council of Canada Operating Grant (MT-15128). Project title: “Mechanisms of akinesia in Parkinson’s disease.” $247,974 (10/1998 to 9/2001)
Dean’s Fund, Faculty of Medicine, University of Toronto. Project title: “Mechanisms of akinesia for Parkinson’s disease.” $10,000 (9/1998 to 8/1999). Principal Investigator
Parkinson’s Disease Foundation (USA). Project title: “Physiologic effects of deep brain stimulation in patients with Parkinson’s Disease.” $51,037 (US$34,987)(5/1999 to 4/2000). Principal Investigator
Canada Foundation for Innovation New Opportunities Award. Project title: “Pathophysiologic Mechanisms of Movement Disorders.” $90,000 (06/1999 to 1/2001). Principal Investigator
Connaught New Staff Matching Grant, University of Toronto. Project title: “Mechanisms of akinesia in Parkinson’s disease.” $30,000 (05/1999 to 04/2001). Principal Investigator
Ontario Innovation Trust. Project title: “Pathophysiologic Mechanisms of Movement Disorders.” $90,000. (4/2000 to 1/2001) Principal Investigator.
Parkinson’s Disease Foundation (USA). “Physiologic effects of deep brain stimulation in patients with Parkinson’s Disease”. $51,730 (US$35,000) (7/2000 to 6/2001). Principal Investigator.
Premier’s Research Excellence Award. Project title: “Physiologic Effects of Deep Brain Stimulation in Parkinson’s Disease.” $150,000 (9/2000 to 8/2003). Principal Investigator.
National Institutes of Health (USA). Project title: “Mechanisms of deep brain stimulation.” $350,100 (US$ 225,000) (1/2001 to 12/2003). Co-Investigator.
Canadian Institutes of Health Research (CIHR) Operating Grant. Project Title: “Pathophysiology of Parkinson’s Disease.” $263,156 (10/2001 to 9/2004). Principal Investigator.
Canadian Institutes of Health Research (CIHR) Operating Grant. Project Title: “The mechanism of action of deep brain stimulation.” $44,591 (4/2002 to 3/2003). Principal Investigator.
Michael J. Fox Foundation for Parkinson’s Research. Project title “An open labeled trial of low frequency repetitive transcranial magnetic stimulation for treatment of dyskinesia.” $40,531 (US$31,250) (9/2003 – 8/2004). Principal Investigator
Canadian Institutes of Health Research (CIHR) Operating Grant. Project Title: “Interactions between inhibitory and excitatory systems in the human motor cortex.” $520,696 (4/2003 to 3/2008). Principal Investigator.
University of Toronto Centre for the Study of Pain/AstraZeneca program. Project title: “Maladaptive and adaptive markers of pain and sensorimotor cortical plasticity following repair of peripheral nerve injuries: A pilot study.” $12,500 (3/2004 – 2/2005). Co-investigator
Michael J. Fox Foundation for Parkinson’s Research. Project title: “Effects of subthalamic nucleus stimulation on sensorimotor integration.” $328,950 (US$250,000) (2/2004 -1/2006). Principal Investigator
National Alliance for Research on Schizophrenia and Depression. Project title: “Treating refractory auditory hallucinations in patients with schizophrenia through enhanced cortical inhibition.” $ 40,000 (US$30,000) (7/2004 – 6/2006) Co-investigator
Canadian Institutes of Health Research (CIHR) Operating Grant. Project title: “Pathophysiology of Parkinson’s disease.” $562,432 (10/2004 – 9/2009). Principal Investigator.
Ontario Mental Health Foundation. “Treating refractory auditory hallucinations in patients with schizophrenia using repetitive transcranial magnetic stimulation.” $136,377 (4/2005 – 3/2006). Co-investigator
Michael J. Fox Foundation for Parkinson’s Research. Project title: “The oscillation model of the basal ganglia.” $573,276 (US$498,750)(5/2006 – 4/2009). Principal Investigator
Canadian Institutes of Health Research (CIHR) Operating Grant. Project title: “Mechanisms of cortical inhibition, facilitation and plasticity in humans.” $943,438 (4/2008 to 3/2013). Principal Investigator.
Alberta Children’s Hospital Foundation. Project title: “Mapping and modulation of brain plasticity in perinatal stroke.” $50,000 (1/2009 to 1/2010). Co-investigator (PI, Dr. Adam Kirton).
Dystonia Medical Research Foundation. Project title: “Effect of internal globus pallidus deep brain stimulation for dystonia on cortical circuits and plasticity.” $170,144.00 (US$130,000) (7/2009 – 6/2011). Principal Investigator
Canadian Institutes of Health Research (CIHR) Operating Grant. Project title: “Pathophysiology of Parkinson’s disease.” $949,900 (10/2009 – 9/2014). Principal Investigator.
Michael J. Fox Foundation for Parkinson’s Research, Clinical Intervention Awards Program. Project title: “Magnetic stimulation for the treatment of motor and mood symptoms of Parkinson’s disease: A 4-center sham-controlled, parallel group study.” $1,545,257 (US$1,498,899) (7/2009-6/2015) Co-Principal Investigator. (PI: Alvaro Pascual-Leone).
Canadian Institutes of Health Research (CIHR) Operating Grant. Project title: “Pathophysiological mechanisms of dystonia: insights from deep brain stimulation and brain plasticity.” $839,082 (10/2012 – 3/2018). Principal Investigator.
Merz Pharma Canada. Investigator Initiated Research. Project title: “Botulinum toxin (Xeomin) for focal hand dystonia: Effects on clinical outcome and cortical plasticity.” $126,000 (12/2012-11/2018). Principal Investigator.
Canadian Institutes of Health Research (CIHR) China-Canada Joint Health Research Initiative. Project title: “Role of the basal ganglia in inhibiting and promoting voluntary movements.” $225,000 (1/2014-12/2016). Principal Investigator
Canadian Institutes of Health Research (CIHR) Operating Grant. Project title: “Pathophysiology of Parkinson’s Disease.” $ 915,575 (10/2014 – 9/2019). Principal Investigator.
Canadian Institutes of Health Research (CIHR) Operating Grant: Industry-partnered (Medtronic Inc.) Collaborative Research. Project title: “Long-term stability of local field potentials recorded from the subthalamic nucleus and effects of deep brain stimulation.” $540,456 (10/2014 – 9/2017). Principal Investigator.
Weston Foundation Rapid Response Grant (PI Dr. Kaviraj Udupa, Neil Drummond). Project title: “Phase-Amplitude Coupling of Local Field Potentials in Subthalamic Nucleus in Parkinson’s disease.” $149,900 (1/2017-7/2019). Role: Administrative Supervisor.
Canadian Institutes of Health Research (CIHR) Foundation Grant. Project title: “Cortical and basal ganglia mechanisms in movement disorders.” $3,268,959 (7/2017 – 6/2025). Principal Investigator.
Dystonia Medical Research Foundation. Project title: “Modulating the functional connectivity of the cerebellum in Musician’s Dystonia.” $81,250 (US$65,000, 11/2017-10/2019).Principal Investigator.
Canada Foundation for Innovation and Ontario Research Fund. Project title: “The CenteR for Advancing Neurotechnological Innovation to Application (CRANIA).” (PI Milos Popovic). $16,350,000 (1/2018-12/2022). Co-applicant.
Canada Foundation for Innovation (John R. Evans Leaders Fund) and Ontario Research Fund. Project title: “Enabling biomarker identification and treatment optimization for prevalent neurological disorders.” $310,523 (11/2018-10/2021). Principal Investigator.
National Institutes of Health R01 Grant. Project title: Stopping behavior and interrupting cognition via subthalamic nucleus (PI: Adam Aron). $4,273,404.7 (USD$3,265,132) Amount for Chen lab $585,099.04 (USD$447,050)(5/2018-4/2023). Co-investigator.
BIAL Foundation. Project Title: Mind-matter interactions and the frontal lobes of the brain (PI: Morris Freedman). EUR 50,000. (5/2019-5/2020). Co-investigator.
PEER-REVIEWED RESEARCH GRANTS -PENDING
National Science and Engineering Research Council (NSERC) Research Tools and Instruments Grant. Project Title: Non-invasive neuromodulation using low-intensity transcranial focused ultrasound in the human brain. $149,954. Principal Investigator.
National Science and Engineering Research Council (NSERC) Discovery Grant. Project Title: Non-invasive neuromodulation using low-intensity transcranial focused ultrasound in the human brain. $149,954. Principal Investigator. $645,743. Principle Investigator.
PEER-REVIEWED SALARY AWARDS
Medical Research Council of Canada Scholarship Award. Project title: “Mechanisms of akinesia in Parkinson’s disease” $296,875 (7/1999 to 6/2004).
Canadian Institutes of Health Research (CIHR) Industry Sponsored Investigator Award (Industry Partner Medtronic Inc). Project Title: “Mechanisms of deep brain stimulation and relationship to oscillations in the basal ganglia”. $375,000. (7/2007 to 6/2012).
PEER-REVIEWED TRAINEE AWARDS
Ontario Mental Health Foundation, Research Training Fellowship (awarded to Dr. Z.J. Daskalakis, research fellow and Ph.D. student). Project title: “A study of Intracortical Inhibition and Facilitation in Schizophrenia Using Transcranial Magnetic Stimulation.” $66,000 (7/1999 to 6/2001). Co-supervisor
Cleghorn Fellowship, University of Toronto (awarded to Dr. Z.J. Daskalakis, research fellow and Ph.D. student). Project title: “A study of Intracortical Inhibition and Facilitation in Schizophrenia Using Transcranial Magnetic Stimulation.” $9,125 (6/2000 to 5/2001). Co-supervisor
Research Training Fellowship, The Ontario Mental Health Foundation (awarded to Dr. Z.J. Daskalakis, research fellow and Ph.D. student) Project title: “A study of cortical inhibition in schizophrenia using transcranial magnetic stimulation.” $35,600 (7/2001 to 6/2002). Co-supervisor
Postdoctoral Fellowship, Canadian Psychiatric Research Foundation (awarded to Dr. Z.J. Daskalakis, research fellow and Ph.D. student). Project title: “A study of cortical inhibition in schizophrenia using transcranial magnetic stimulation.” $60,000 (7/2001 to 6/2003). Co-supervisor
Canadian Institutes of Health Research (CIHR) Doctoral Research Award (awarded to Gregory Molnar, Ph.D. student). Project Title: “Neurophysiological assessment of deep brain stimulation in Parkinson’s disease and essential tremor patients.” $ 60,000 (6/2001 to 5/2004). Supervisor.
Canadian Institutes of Health Research (CIHR) Clinician Scientist award (awarded to Dr. Z.J. Daskalakis). Project Title: “A study of cortical inhibition and plasticity using transcranial magnetic stimulation.” $160,500 (7/2002 to 6/2006). Co-supervisor.
Dystonia Medical Research Foundation – Dystonia Fellowship award (awarded to Dr. A. Espay, Clinical Fellow). Project title “Pathophysiology of psychogenic dystonia.” USD $80,000 (7/2003 – 6/2005). Supervisor.
Canadian Institutes of Health Research (CIHR) fellowship award (awarded to Dr. Aimee J. Nelson, Postdoctoral Fellow). Project title: “Sensorimotor processing in cortical and subcortical loci in dystonia patients.” $135,000 (9/2005 – 8/2008). Supervisor.
Canadian Institutes of Health Research (CIHR) Clinician Scientist award renewal (awarded to Dr. Z.J. Daskalakis). Project Title: “A study of cortical inhibition and plasticity using transcranial magnetic stimulation.” $57,500 (7/2006 to 6/2007). Co-supervisor.
Canadian Institutes of Health Research (CIHR) Frederick Banting and Charles Best Canada Graduate Scholarships – Doctoral Award (awarded to E. Tsang, PhD student). Project title: “Discovery of the mechanism of deep brain stimulation for the treatment of Parkinson’s disease.” $70,000 (5/2008 to 4/2010). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship in the areas of dystonia in Partnership with CIHR Institute of Neuroscience, Mental Health & Aging and Dystonia Medical Research Foundation of Canada (awarded to Z. Ni, postdoctoral fellow). Project title: “The Neuronal Origin of Voluntary Drive and its Expression in Human Motor Cortex.” $90,000 (7/2008 to 6/2010). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship in the areas of dystonia in Partnership with CIHR Institute of Neuroscience, Mental Health & Aging and Dystonia Medical Research Foundation of Canada (awarded to B. Elahi, postdoctoral fellow). Project title: “Regulatory effect of intra cortical inhibition on Paired Associative Stimulation (PAS) induced sensory-dependent, motor cortex plasticity.” $112, 500 (5/2009 to 10/2011). Supervisor.
Canadian Institutes of Health Research (CIHR) Maters Award: Fredrick Banting and Charles Best Canada Graduate Scholarships (awarded to N. Bahl, MSc student). Project title: “Plastic changes in Parkinson disease patients with deep brain stimulation implants.” $17,500 (9/2010 to 8/2011). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship in the areas of dystonia in Partnership with CIHR Institute of Neuroscience, Mental Health & Aging and Dystonia Medical Research Foundation of Canada (awarded to A. Yugeta, postdoctoral fellow). Project title: “Saccade-related beta band activity in local field potentials recorded from human basal ganglia.” $90,000 (4/2011 to 3/2013). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship in the areas of dystonia in Partnership with CIHR Institute of Neuroscience, Mental Health & Aging and Dystonia Medical Research Foundation of Canada (awarded to K. Udupa, postdoctoral fellow). Project title: “Prediction of clinical improvement by deep brain stimulation surgery in primary generalized dystonia using clinical, genetics and neurophysiologic measures.” $127,500 (4/2011 to 1/2014). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship in the areas of dystonia in Partnership with CIHR Institute of Neuroscience, Mental Health & Aging and Dystonia Medical Research Foundation of Canada (awarded to R. Cash, postdoctoral fellow). Project title: “A novel brain stimulation intervention to investigate the pathophysiology and modulate plasticity in dystonia.” $90,000 (4/2012 to 3/2014). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship in the areas of dystonia in Partnership with CIHR Institute of Neuroscience, Mental Health & Aging and Dystonia Medical Research Foundation of Canada (awarded to R. Isayama, postdoctoral fellow). Project title: “Exploring the Premotor and the Parietal Connectivity with Primary Motor Cortex during the Rubber Hand Illusion in Focal Hand Dystonia.” $135,000 (5/2013 to 4/2016). Supervisor.
Parkinson Society of Canada Basic Research Fellowship (awarded to Natasha Radhu, postdoctoral fellow). Project title: “Interactions between motor cortical inhibitory and excitatory circuits in Parkinson’s disease using transcranial magnetic stimulation.” $80,000 (11/2015 to 10/2017). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship Award (awarded to Matt Brown, postdoctoral fellow). Project title: “Induction of neural plasticity in motor preparatory areas using novel transcranial magnetic stimulation (TMS) techniques.” $135,000 (6/2015 to 4/2018). Supervisor.
Dystonia Coalition Career Development Award (awarded to Dr. Kaviraj Udupa, postdoctoral fellow). Project title: “Phase-amplitude of local field potentials in internal globus pallidus in dystonia.” $64,102 (US$50,000)(9/2016-8/2017). Supervisor.
Canadian Institutes of Health Research 2017 Canada Graduate Scholarships-Master’s (CGS M) Competition (awarded to James Saravanamuttu, MSc student). Project title “Interaction between cortical circuits in Parkinson’s disease.” $17,500.00 (09/2016-08/2017). Supervisor.
Parkinson Canada Clinical Research Fellowship (awarded to Dr. Reina Isayama, clinical fellow). Project title: “Detailed mapping of the cortical projections of the subthalamic nucleus in Parkinson’s disease.” $100,000 (7/2016-6/2018). Supervisor.
Canadian
Institutes of Health Research (CIHR) Doctoral Award (awarded to Julianne
Baarbe, PhD student). Project title: “Exploring parietal-motor connectivity for
freezing of gait in Parkinson’s disease” $105,000 (9/2016-8/2019). Supervisor
Parkinson Canada Basic Research Fellowship (awarded to Dr. Michael Vesia, postdoctoral fellow). Project title: “Sensorimotor Connectivity in Parkinson’s disease: Bridging Neuroimaging, Neurophysiology, and Treatment.” $100,000 (10/2016-9/2018). Supervisor.
Krembil Fellowship Award (awarded to Neil Drummond, postdoctoral fellow). Project title “Long-term stability of local field potentials recorded from the subthalamic nucleus and the effects of deep brain stimulation.” $30,000 (9/2017-8/2018). Supervisor
Parkinson Canada Graduate Student Award (awarded to Cricia Rinchon, MSc student. Project title: “Plasticity Induction in Chronic Deep Brain Stimulation Patients with Parkinson’s Disease.” $30,000 (9/2017- 8/2019). Supervisor.
Canadian Institutes of Health Research (CIHR) Fellowship Award (awarded to Neil Drummond, postdoctoral fellow). Project title: “Uncovering how cortical and subcortical inhibitory brain structures contribute to uncontrollable freezing of movement in Parkinson’s disease.” $90,000 (4/2019 to 3/2021). Supervisor.
Krembil Fellowship Award (awarded to Ghazaleh Darmani, postdoctoral fellow). Project title “Investigating deep brain stimulation‐induced plasticity in Parkinson’s disease by concurrent transcranial magnetic stimulation and electroencephalography (TMS‐EEG).” $30,000 (9/2019-8/2020). Supervisor
Parkinson Canada Graduate Student Award (awarded to Stephanie Tran, MSc student. Project title: “Characterizing the effects of Parkinson’s disease on multisensory integration for balance.” $20,000 (8/2019-7/2021). Supervisor.
PUBLICATIONS (total: 307, H-index 86; total citations 28,410, Google Scholar, November 27, 2019)
Peer-reviewed Papers
1. Chen REW, Loke YW. Antibody isotype produced by pregnant mice immunized with fetal allogenic lymphocytes is mainly IgG1. Journal of Reproductive Immunology 1987;10:189-199.
2. Chen R, Ashby P, Lang AE. Stimulus-sensitive myoclonus in akinetic rigid syndromes. Brain 1992;115:1875-1888.
3. Chen R, Matthews JH, Jackson AC. Large granular lymphoproliferative disease associated with nephrotic syndrome, renal failure, and leukoencephalopathy. Leukemia and Lymphoma, 1993;11:129-133.
4. Chen R, Ashby P. Reflex responses in upper limb muscles to cutaneous stimuli. Canadian Journal of Neurological Sciences 1993;20:271-278.
5. Chen R, Ramsay DA, deVeber LL, Assis L, Levin SD. Immunosuppressive measles encephalitis. Pediatric Neurology 1994;10:325-327.
6. Chen R, Sahjpaul R, Del Maestro RF, Assis L, Young GB. Initial enlargement of the opposite pupil as a false localizing sign in intraparenchymal frontal haemorrhage. Journal of Neurology, Neurosurgery and Psychiatry 1994;57:1126-1128.
7. Chen R, Collins SJ, Remtulla H, Parkes A, Bolton CF. Phrenic nerve conduction studies in normal subjects. Muscle and Nerve 1995;18:330-335.
8. Chen R, Remtulla H, Bolton CF. Electrophysiological study of diaphragmatic myoclonus. Journal of Neurology, Neurosurgery and Psychiatry 1995;58:480-483.
9. Chen R, Macdonald DR, Ramsay DA. Primary diffuse leptomeningeal oligodendroglioma. Journal of Neurosurgery 1995;83:724-728.
10. Chen R, Collins SJ, Remtulla H, Parkes A, Bolton CF. Needle EMG of the human diaphragm: Power spectral analysis in normal subjects. Muscle and Nerve 1996;19:324-330.
11. Zifko U, Chen R, Remtulla H, Hahn AF, Koopman W, Bolton CF. Respiratory electrophysiological studies in Guillan-Barré syndrome. Journal of Neurology, Neurosurgery and Psychiatry 1996;60:191-194.
12. Chen R, Grand’Maison F, Strong MJ, Ramsay DA, Bolton CF. Motor neuron disease presenting as acute respiratory failure: a clinical and pathological study. Journal of Neurology, Neurosurgery and Psychiatry 1996;60:455-458.
13. Chen R, Bolton CF, Young GB. Prediction of outcome in anoxic coma: A clinical and electrophysiological study. Critical Care Medicine 1996;24:672-678.[Published erratum appears in Critical Care Medicine, 24:1277]
14. Nicolle MW, Stewart DJ, Remtulla H, Chen R, Bolton CF. Lambert-Eaton myasthenic syndrome presenting with severe respiratory failure. Muscle and Nerve 1996;19:1328-1333.
15. Bolton CF, McKeown MJ, Chen R, Toth B, Remtulla H. Subacute uremic and diabetic polyneuropathy.Muscle and Nerve 1997;20:59-64.
16. Chen R, Gerloff C, Hallett M, Cohen LG. Involvement of the ipsilateral motor cortex in finger movements of different complexities. Annals of Neurology 1997;41:247-254.
17. Chen R, Grand’Maison F, Bolton CF. Motor neuron disease presenting as acute respiratory failure: Electrophysiological studies. Muscle and Nerve 1997;20:517-519.
18. Chen R, Classen J, Gerloff C, Celnik P, Wassermann WM, Hallett M, Cohen LG. Depression of motor cortex excitability by low frequency transcranial magnetic stimulation. Neurology 1997;48:1398-1403.
19. Collins SJ, Chen R, Remtulla H, Parkes A, Bolton CF. Novel measurement for automated interference pattern analysis of the diaphragm. Muscle and Nerve 1997;20:1038-1040.
20. Chen R, Samii A, Caños M, Wassermann EM, Hallett M. Effects of phenytoin on cortical excitability. Neurology 1997;49:881-883.
21. Chen, R, Wassermann EM, Caños M, Hallett M. Impaired inhibition in writer’s cramp during voluntary muscle activation.Neurology 1997;49:1054-1059.
22. Chen R, Cohen LG, Hallett M. Role of the ipsilateral motor cortex in voluntary movement. Canadian Journal of Neurological Sciences 1997;24:284-291.
23. Chen R, Gerloff C, Classen J, Wassermann EM, Hallett M, Cohen LG. Safety of different inter-train intervals for repetitive transcranial magnetic stimulation and recommendations for safe ranges of stimulus parameters. Electroencephalography and Clinical Neurophysiology 1997;105:415-421.
24. Gerloff C, Corwell B, Chen R, Hallett M, Cohen LC. Stimulation over the human supplementary motor area interferes with the organization of future elements in complex motor sequences. Brain 1997;120:1587-1602.
25. Samii A, Chen R, Wassermann EM, Hallett M. Phenytoin does not influence post-exercise facilitation of motor evoked potentials. Neurology 1998;50:291-293.
26. Chen R. Electrophysiological studies in the critical care unit: Investigating polyneuropathies. Canadian Journal of Neurological Sciences 1998;25:S32-35.
27. Chen R, Corwell B, Yaseen Z, Hallett M, Cohen LG. Mechanisms of cortical reorganization in lower-limb amputees. The Journal of Neuroscience 1998;18:3443-3450.
28. Chen R, Yaseen Z, Cohen LG, Hallett M. The time course of corticospinal excitability in reaction time and self-paced movements. Annals of Neurology 1998;44:317-325.
29. Gerloff C, Cohen LG, Floeter MK, Chen R, Corwell B, Hallett M. Inhibitory influence of the ipsilateral motor cortex on responses evoked by transcranial stimulation of the human cortex and pyramidal tract. Journal of Physiology (Lond) 1998;510:249-259.
30. Chmielowska J, Coghill RC, Maisog JM, Carson RE, Herscovitch P, Honda H, Chen R, Hallett M. Positron emission tomography [15O]water studies with short interscan interval for single-subject and group analysis: influence of background subtraction. Journal of Cerebral Blood Flow and Metabolism 1998;18:433-443
31.Gerloff C, Corwell B, Chen R, Hallett M, Cohen LG. The role of the human motor cortex in the control of complex and simple finger movement sequences. Brain 1998;121:1695-1709.
32. Cohen LG, Ziemann U, Chen R, Classen J, Hallett M, Gerloff C, Butefisch B. Studies of neuroplasticity with transcranial magnetic stimulation. Journal of Clinical Neurophysiology 1998;15:305-324.
33. Wassermann EM, Wedegaertner FR, Ziemann U, George MS, Chen R. Crossed reduction of motor cortex excitability by 1 Hz transcranial magnetic stimulation. NeuroscienceLetters 1998;250:141-144.
34. Ziemann U, Chen R, Cohen LG, Hallett M. Dextromethorphan decreases the excitability of the human motor cortex. Neurology 1998;51:1320-1324.
35. Chen R, Tam A, Butefisch C, Corwell B, Ziemann U, Rothwell JC, Cohen LG. Intracortical inhibition and facilitation in different representations of the human motor cortex. Journal of Neurophysiology 1998;80:2870-2881.
36. Chen R, Karp BI, Hallett M. Botulinum toxin type F for treatment of dystonia: long-term experience. Neurology 1998;51:1494-1496.
37. Chen R, Karp BI, Goldstein SR, Bara-Jimenez W, Yaseen Z, Hallett M. Effect of muscle activity immediately after botulinum toxin injection for writer’s cramp. Movement Disorders 1999;14:307-312.
38. Kumar R, Chen R, Ashby P. Safety of transcranial magnetic stimulation in patients with implanted deep brain stimulators. Movement Disorders 1999;14:157-158.
39. Chmielowska J, Coghill RC, Carson RD, Ishii K, Chen R, Herscovitch P, Hallett M. Comparison of PET [150] water studies with 6-minute and 10-minute interscan intervals: single subject and group analyses. Journal of Cerebral Blood Flow and Metabolism 1999;19:570-582.
40. Karp BI, Goldstein S, Chen R, Samii A, Bara-Jimenez W, Hallett M. An open trial of clozapine for dystonia. Movement Disorders 1999;14:652-657
- Chen R, Corwell B, Hallett M. Modulation of motor cortex excitability by median
nerve and digit stimulation. Experimental Brain Research 1999;129:77-86.
- Chen R, Hallett M. The time course of changes in motor cortex excitability associated with voluntary movement. Canadian Journal of Neurological Sciences 1999;26:163-169.
43. Chen R, Lozano AM, Ashby P. Mechanism of the silent period following transcranial magnetic stimulation: evidence from epidural recordings. Experimental Brain Research 1999;128:539-542.
44. Ashby P, Chen R, Wennberg R, Lozano AM, Lang AE. Cortical reflex myoclonus studied with cortical electrodes. Clinical Neurophysiology 1999;110:1521-1530.
44. Classen J, Steinfelder B, Liepert J, Stefani K, Celnik P, Cohen LG, Hess A, Kunesch E, Chen R, Benecke R, Hallett M. Cutaneomotor integration in humans is somatotopically organized at various levels of the nervous system and is task dependent. Experimental Brain Research 2000;130:48-59.
46. Chen R, Garg R. Facilitatory I wave interaction in proximal arm and lower limb muscle representation of the human motor cortex. Journal of Neurophysiology 2000;83:1426-1434.
47. Chen R. Studies of human motor physiology with transcranial magnetic stimulation. Muscle & Nerve 2000;23(Suppl 9):S26-S32.
48. Fine J, Duff J, Chen R, Hutchison W, Lozano AM, Lang AE. Long-term follow-up of unilateral posteroventral medial pallidotomy in advanced Parkinson’s Disease. New England Journal of Medicine 2000;342:1708-1714.
49. Boroojerdi B, Ziemann U, Chen R, Butefisch C, Cohen LG. Mechanisms underlying human motor system plasticity. Muscle & Nerve 2001;24:602-613
50. Sanger T, Garg RR, Chen R. Interactions between two different inhibitory systems in the human motor cortex. Journal of Physiology 2001;530:307-317.
52. Chen R, Kumar S, Garg RR, Lang AE. Impairment of motor cortex activation and deactivation in Parkinson’s Disease. Clinical Neurophysiology 2001;112:600-607.
53. Pierpaoli C, Barnett A, Chen R, Penix L, Virta A, Basser P. Water diffusion changes in Wallerian degeneration and their dependence on white matter architecture. Neuroimage 2001;13:1174-1185.
54. Ashby P, Paradiso G, Saint Cyr J, Chen R, Lang A, Lozano A. Potentials evoked at the scalp by stimulation near the human subthalamic nucleus. Clinical Neurophysiology 2001;112:431-437.
55. Sundara M,Namasivayam AK, Chen R. Observation-execution matching system for speech: A magnetic stimulation study. Neuroreport 2001;12:1341-1344.
56.Chen R, Sietz RJ. Changing cortical excitability with low frequency magnetic stimulation.Neurology 2001;57:379-380 (invited Editorial).
57. Pinto AD, Chen R. Suppression of the motor cortex by magnetic stimulation of the cerebellum. Experimental Brain Research 2001;140:505-510.
58. Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S. Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation. Archives of General Psychiatry 2002;59:347-354.
59. Paradiso G, Khan F, Chen R. Effects of apomorphine on flexor reflex and periodic limb movement. Movement Disorders 2002;17:594-597.
60. Daskalakis ZJ, Christensen BK, Fitzgerald PB, Chen R. Transcranial magnetic stimulation: a new investigational and treatment tool in psychiatry. Journal of Neuropsychiatry and Clinical Neuroscience 2002;14:406-415. (review)
61. Chen R, Cohen LG, Hallett M. Nervous system reorganization following injury.Neuroscience 2002;111:761-773. (review)
62. Cunic D, Roshan L, Khan F, Lozano AM, Lang AE, Chen R. Effects of subthalamic nucleus stimulation on motor cortex excitability in Parkinson’s disease. Neurology 2002;58: 1665-1672.
63. Fitzgerald PB, Brown TL, Daskalakis ZJ, Chen R, Kulkarni J. Intensity dependent effects of 1Hz rTMS on human corticospinal excitability. Clinical Neurophysiology 2002;113:1136-1141.
64. Daskalakis ZJ, Christensen BK, Fitzgerald PB, Roshan L, Chen R. The mechanisms of interhemispheric inhibition in the human motor cortex. Journal of Physiology 2002;543: 317-326.
65. Lozano AM, Jonathan J, Chen R, Ashby P. Deep brain stimulation for Parkinson’s disease: Disrupting the disruption. Lancet Neurology 2002;1:225-231.
66.Theodore WH, Hunter K, Chen R, Vega-Bermudez F, Boroojerdi B, Reeves-Tyer P, Werhahn K, Kelley K, Cohen L. Transcranial magnetic stimulation for the treatment of seizures: A controlled study. Neurology 2002;59:560-562.
67. Sailer A, Molnar GF, Cunic DI, Chen R. Effects of peripheral sensory input on cortical inhibition. Journal of Physiology 2002;544:617-629.
68. Levy L, Ziemann U, Chen R, Cohen LG. Rapid modulation of GABA in sensorimotor cortex induced by acute deafferentation. Annals of Neurology 2002;52:755-761.
69. Wennberg R, Pohlmann-Eden B, Chen R, Lozano A. Combined scalp-thalamic EEG recording in sleep and epilepsy. Clinical Neurophysiology 2002;113:1867-1869.
70. Daskalakis ZJ, Molnar GF, Sailer A, Christensen BK, Fitzgerald PB, Chen R. An automated method to determine the transcranial magnetic stimulation (TMS) induced silent period. Clinical Neurophysiology 2003;114:938-944.
71. Wittenberg GF, Chen R, Ishii K, Bushara KO, Eckloff S, Croarkin E, Taub E, PhD, Gerber LH, Hallett M, Cohen LG. Constraint-Induced therapy in stroke: magnetic-stimulation motor maps and cerebral activation. Neurorehabilitation and Neural Repair 2003;17:48-57.
72. Chen R, Yung D, Li J-Y. Organization of ipsilateral excitatory and inhibitory pathways in the human motor cortex. Journal of Neurophysiology 2003;89:1256-1264.
73. Roshan L, Paradiso G, Chen R. Two phases of short interval intracortical inhibition. Experimental Brain Research 2003;151:330-337.
74. Pinto AD, Lang AE, Chen R. The cerebellothalamocortical pathway in essential tremor. Neurology 2003;60:1985-1987.
75. Sailer A, Molnar GF, Paradiso G, Lang AE, Chen R. Short and long latency afferent inhibition in Parkinson’s disease. Brain 2003;126:1883-1894.
76. Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S. Effect of antipsychotics on cortical inhibition using transcranial magnetic stimulation. Psychopharmacology (Berl) 2003;170:255-262.
77. Chen R, Haywood CT, Mikulis DJ, Manktelow RT, Anastakis DJ. Plasticity of the human motor system following muscle reconstruction: A magnetic stimulation and fMRI study. Clinical Neurophysiology 2003;114:2434-2446.
78. Paradiso G, Saint-Cyr JA, Lozano AM, Lang AE, Chen R. Involvement of the human subthalamic nucleus in movement preparation. Neurology 2003;61:1538-1545.
79. Chen R. Interactions between inhibitory and excitatory circuits in the human motor cortex. Experimental Brain Research 2004;154:1-10.
80. Hanajima R, Dostrovsky JO, Lozano AM, Hutchison WD, Davis KD, Chen R, Ashby P. Somatosensory evoked potentials recorded from deep brain stimulation electrodes in the thalamus and subthalamic nucleus. Clinical Neurophysiology 2004;115:424-434.
82. Molnar GF, Sailer A, Gunraj CA, Lang AE, Lozano AM, Chen R. Thalamic deep brain stimulation activates the cerebellothalamocortical pathway. Neurology 2004;63:907-909.
83. Hanajima R, Ashby P, Lozano AM, Lang AE, Chen R. Single pulse stimulation of the human subthalamic nucleus facilitates the motor cortex at short intervals. Journal of Neurophysiology 2004;92:1937-1943.
84. Paradiso G, Cunic D, Chen R. Involvement of subcortical structures in the preparation of self-paced movement. Journal of Psychophysiology 2004;18:130-139.
85. Chen R, Lemon R. Subthalamic nucleus and gait disturbance: interactions between basal ganglia and brainstem and spinal pathways? Neurology 2004; 63:1150-1151.
86. Paradiso G, Cunic D, Saint-Cyr JA, Hoque T, Lozano AM, Lang AE, Chen R. Involvement of human thalamus in the preparation of self-paced movement. Brain 2004; 127: 2717-2731.
87. Hanajima R, Chen R, Ashby P, Lozano AM, Hutchison WD, Davis KD, Dostrovsky JO. Very fast oscillations evoked by median nerve stimulation in the human thalamus and subthalamic nucleus. Journal of Neurophysiology 2004; 92:3171-3182
88. Daskalakis ZJ, Christensen BK, Fitzgerald PB, Fountain SI, Chen R. Reduced cerebellar inhibition with schizophrenia: a preliminary study. American Journal of Psychiatry 2005; 162: 203-1205.
89. Bütefisch CM, Boroojerdi B, Chen R, Battaglia F, Hallett M. Task dependent intracortical inhibition is impaired in focal hand dystonia. Movement Disorders 2005; 20: 545-561.
90. Kukaswadia S, Wagle-Shukla A, Morgante F, Gunraj C, Chen R. Interactions between long latency afferent inhibition and interhemispheric inhibitions. Journal of Physiology 2005; 563: 915-924.
91. Molnar GF, Sailer A, Gunraj CA, Cunic DI, Lang AE, Lozano AM, Moro E, Chen R. Changes in cortical excitability with thalamic deep brain stimulation. Neurology 2005; 64:1913-1919.
92. Espay AJ, Li J-Y, Johnston L, Chen R, Lang AE. Mirror movements in Parkinsonism: evaluation of a new clinical sign. Journal of Neurology, Neurosurgery and Psychiatry 2005; 76:1355-1358.
93. Pal PK, Hanajima R, Gunraj C, Li J-Y,Wagle-Shukla A, Morgante F, Chen R. Effect of low frequency repetitive transcranial magnetic stimulation on interhemispheric inhibition. Journal of Neurophysiology 2005; 94:1668-1675.
94. Paradiso G, Cunic DI, Gunraj CA, Chen R. Representation of facial muscles in human motor cortex. Journal of Physiology 2005; 567: 323-336.
95. Gerloff C, Bushara K, Sailer A, Wassermann EM, Chen R, Matsuoka T, Waldvogel D, Wittenberg GF, Ishii K, Cohen LG, Hallett M. Multimodal imaging of brain reorganization in motor areas of the contralesional hemisphere of well recovered patients after capsular stroke. Brain 2006; 129: 791-808.
96. HanajimaR, Lozano AM, Dostrovsky JO, Chen R. Dissociation of thalamic high frequency oscillations and slow components of sensory evoked potentials following damage to ascending pathways. Clinical Neurophysiology 2006; 117: 906-911.
97. Morgante F, Espay AJ, Gunraj C, Lang AE, Chen R. Motor cortex plasticity in Parkinson’s disease and levodopa-induced dyskinesias. Brain 2006; 129: 1059-1069.
98. Molnar GF, Sailer A, Gunraj CA, Cunic DI, Wennberg R, Lozano AM, Chen R. Changes in motor cortex excitability with stimulation of anterior thalamus in epilepsy. Neurology 2006; 66: 566-571.
99. Espay AJ, Morgante F, Pruzner J, Gunraj C, Lang AE, Chen R. Cortical and spinal abnormalities in psychogenic dystonia. Annals of Neurology 2006; 59: 825-834.
100. Espay AJ, Morgante F, Gunraj C, Chen R, Lang AE. Mirror movements in Parkinson’s disease: effect of dopaminergic medications. Journal of Neurology, Neurosurgery and Psychiatry 2006; 77: 1194-1195.
101. Daskalakis ZJ, Möller B, Christensen BK, Fitzgerald PB, Gunraj C, Chen R. The effects of repetitive transcranial magnetic stimulation on cortical inhibition in healthy human subjects. Experimental Brain Research 2006; 174: 403-412.
102. Espay AJ, Chen R. Rigidity and spasm from autoimmune myelopathies: the Stiff-Person syndrome. Muscle and Nerve 2006; 24: 677-690.
103. Espay AJ, Bergeron C, Chen R, Lang AE. Rapidly progressive sporadic dentatorubralpallidoluysian atrophy with intracytoplasmic inclusions and no CAG repeat expansion. Movement Disorders 2006; 21: 2251-2254.
104. Fawcett AP, Cunic D, Hamani C, Hodaie M, Lozano AM, Chen R, Hutchison WD. Saccade-related potentials recorded from human subthalamic nucleus. Clinical Neurophysiology 2007; 118: 155-163.
105. Sailer A, Cunic DI, Paradiso GO, Gunraj CA, Wagle-Shukla A, Moro E, Lozano AM, Lang AE, Chen R. Subthalamic deep brain stimulation modulates afferent inhibition in Parkinson’s disease. Neurology 2007; 68: 356-363.
106. Wagle-Shukla A, Angel MJ; Zadikoff C, Enjati M, Gunraj CA, Lang AE, Chen R. Low frequency repetitive transcranial magnetic for treatment of levodopa-induced dyskinesias. Neurology 2007; 68: 704-705.
107. Li J-Y, Espay AJ, Gunraj C, Pal PK, Cunic DI, Lang AE, Chen R. Interhemispheric and ipsilateral connections in Parkinson’s disease: relation to mirror movements. Movement Disorders 2007; 22: 813-812.
108. Harris-Love ML, Chen R, Cohen LG. Interhemispheric inhibition in distal and proximal arm representations in the primary motor cortex. Journal of Neurophysiology 2007; 97: 2511-2515.
109. de Bie RMA, Chen R, Lang AE. Orthostatic tremor in progressive supranuclear palsy. Movement Disorders 2007; 22:1192-1194.
110. Tang JKH, Mahant N, Cunic D, Chen R, Moro E, Lang AET, Lozano AM, Hutchison WD, Dostrovsky JO. Changes in cortical and pallidal oscillatory activity during the execution of a sensory trick in patients with cervical dystonia. Experimental Neurology2007; 204: 845-848.
111. Lee H, Gunraj C, Chen R. The effects of excitatory and facilitatory intracortical circuits on interhemispheric inhibition in the human motor cortex. Journal of Physiology 2007; 580: 1021-1032.
112. Márquez Chin C, Popovic MR, Thrasher A, Cameron T, Lozano A, Chen R. Identification of arm movements using correlation of electrocorticographic spectral components and kinematic recordings.Journal of Neural Engineering 2007; 4:146-158.
113. Espay AJ, Fox SH, Marras C, Lang AE, Chen R, Isolated diaphragmatic tremor: is there a spectrum in “diaphragmatic myoclonus”? Neurology 2007; 69: 689-692.
114. Purzner P, Paradiso GO, Cunic D, Saint-Cyr JA, Hoque T, Lozano AM, Lang AE, Moro E, Hodaie M, Mazzella F, Chen R. Involvement of the basal ganglia and cerebellar motor pathways in the preparation of self-initiated and externally triggered movements in humans. The Journal of Neuroscience 2007; 27: 6029-6036.
115. Möller BM, Light GA, Fitzgerald PB, Snyder JS, Chen R, Daskalakis ZJ. Relationship between P50 suppression and the cortical silent period. Neuroreport2007; 18: 1503-1506.
116. Ni Z, Gunraj C, Chen R. Short interval intracortical inhibition and facilitation during the silent period in human. Journal of Physiology 2007; 583: 971-982.
117. Frantseva MV, Fitzgerald PB, Chen R, Möller B, Daigle M, Daskalakis ZJ. Evidence for impaired long-term potentiation in schizophrenia and its relationship to motor skill leaning. Cerebral Cortex 2008; 18: 990-996.
118. Chu J, Gunraj C, Chen R. Possible differences between the time courses of presynaptic and postsynaptic GABAB mediated inhibition in the human motor cortex. Experimental Brain Research 2008; 184:571-577.
119. Daskalakis ZJ, Christensen BK, Fitzgerald PB, Chen R. Dysfunctional neural plasticity in patients with schizophrenia. Archives of General Psychiatry 2008; 65: 378-385.
120. Chen R, Cros D, Curra A, Di Lazzaro V, Lefaucheur J-P, Magistris MR, Mills K, Rösler, KM, Triggs WJ, Ugawa Y, Ziemann U. The clinical diagnostic utility of transcranial magnetic stimulation: Report of an IFCN committee. Clinical Neurophysiology 2008; 119: 504-532.
121. Nelson AJ, Chen R. Digit somatotopy within cortical areas of the postcentral gyrus in humans. Cerebral Cortex 2008; 18: 2341-2351.
122. Daskalakis ZJ, Christensen BK,
Fitzgerald, PB, Möller B, Fountain SI, Chen R.
Increased cortical inhibition in persons with schizophrenia treated with
clozapine. Journal of Psychopharmacology2008; 22: 203-209.
123. Daskalakis ZJ, Farzan F, Barr MS, Maller JJ, Chen R, Fitzgerald PB. Long interval cortical inhibition from the dorsolateral prefrontal cortex: A TMS-EEG Study. Neuropsychopharmacology 2008; 33: 2860-2869.
124. Kirton A, Chen R, Friefeld S, Gunraj C, Pontigon AM, deVeber G. Contralesional repetitive transcranial magnetic stimulation for chronic hemiparesis in subcortical pediatric stroke: a randomized trial. Lancet Neurology 2008, 7: 507-513.
125. Pal PK, Gunraj CA, Li, J-Y, Lang AE, Chen R. Reduced intracortical and interhemispheric inhibitions in corticobasal syndrome. Journal of Clinical Neurophysiology 2008, 25: 304-312.
126. Ni Z, Chen R. Short-interval intracortical inhibition: A complex measure (Editorial). Clinical Neurophysiology 2008; 119 2172-2176.
127. Berardelli A, Abbruzzese G, Chen R, Orth M, Ridding MC, Stinear C, Suppa A, Trompetto C, Thompson PD. Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders. Brain Stimulation 2008; 1: 183-191.
128. Espay AJ, Duker AP, Chen R, Okun MS, Barrett ET, Devoto J, Zeilman P, Gartner M, Burton N, Miranda HA, Mandybur GT, Zesiewicz TA, Foote KD, Revilla FJ. Deep brain stimulation of the ventral intermediate nucleus of the thalamus in medically refractory orthostatic tremor: Preliminary observations. Movement Disorders 2008; 23: 2357-2362.
130. Kirton A, deVeber G, Gunraj, C, Chen R. Neurocardiogenic syncope complicating pediatric transcranial magnetic stimulation. Pediatric Neurology 2008; 39: 196-197.
131. Li J-Y, Cunic DI, Paradiso G, Gunraj C,Pal PK, Lang AE,Chen R. Electrophysiological features of myoclonus-dystonia. Movement Disorders 2008; 23: 2055-2061.
132. Hoppenbrouwers SS, Schutter DJLG, Fitzgerald PB, Chen R, Daskalakis ZJ. The role of the cerebellum in the pathophysiology and treatment of neuropsychiatric Disorders: A Review. Brain Research Reviews 2008; 59: 185-200.
133. Aanstakis DJ, Malessy MJA, Chen R, Davis KD, Mikulis D. Cortical plasticity following nerve transfer in the upper extremity. Hand Clinics 2008; 24: 425-444.
134. Liu SK, Fitzgerald PB, Daigle M, Chen R, Daskalakis ZJ. The relationship between cortical inhibition, antipsychotic treatment and the symptoms of schizophrenia. Biological Psychiatry 2009; 65: 503-509.
135. Elahi B, Elahi B, Chen R. Effect of transcranial magnetic stimulation on Parkinson motor function – Systematic review of controlled clinical trials. Movement Disorders 2009; 24: 357-363.
136. Ni Z, Gunraj C, Nelson AJ, Yeh I-J, Castillo G, Hoque T, Chen R. Two phases of interhemispheric inhibition between motor related cortical areas and the primary motor cortex in human. Cerebral Cortex 2009; 19: 1654-1665.
137. Farzan F, Barr M, Wong W, Chen R, Fitzgerald P, Daskalakis ZJ. Suppression of gamma oscillation in the dorsolateral prefrontal cortex following long interval cortical inhibition: a TMS-EEG Study. Neuropsychopharmacology2009; 34: 1543-1551.
138. Kirton A, Gunraj C, Chen R. TMS neuro-cardiovascular coupling with transcranial magnetic stimulation for diagnosis of vascular compression cranial neuropathy. Canadian Journal Neurological Sciences 2009; 36:83-88
139. Espay AJ, Beaton DE, Morgante F, Gunraj CA, Lang AE, Chen R. Impairments of speed and amplitude of movement in Parkinson’s disease: a pilot study. Movement Disorders 2009; 24: 1001-1008.
141. Udupa K, Chen R. Measurement and modulation of brain plasticity of the motor system in humans using transcranial magnetic stimulation. Motor Control 2009; 13: 442 -453.
142. Nelson AJ, Blake DT, Chen R. Digit-specific aberrations in the primary somatosensory cortex in writer’s cramp. Annals of Neurology 2009; 66: 146-154.
143. Lim SY, Mason WP, Young NP, Chen R, Bower JH, McKeon A, Pittock SJ, Lang AE. Polymyoclonus, laryngospasm, and cerebellar ataxia associated with adenocarcinoma and multiple neural cation channel autoantibodies. Archives of Neurology 2009; 66: 1285-1287.
144. Nelson AJ, Hoque T, Gunraj C, Ni Z, Chen R. Bi-directional interhemispheric inhibition during unimanual sustained contractions. BMC Neuroscience 2009; 10: 31.
145. Márquez-Chin C, Popovic MR, Cameron T, Lozano AM, Chen R. Control of a neuroprosthesis for grasping using off-line classification of electrocorticographic signals: Case Study. Spinal Cord 2009; 47: 802-808.
146. Leung A, Donohue M, Xu R, Lee R, Lefaucheur JP, Khedr EM, Saitoh Y, André-Obadia N, Rollnik J, Wallace M, Chen R. rTMS for suppressing neuropathic pain: A Meta-Analysis. The Journal of Pain 2009; 10: 1205-216.
147. Ballanger B, Lozano AM, Moro E, van Eimeren T, Hamani C, Chen R, Cilia R, Houle S, Poon YY, Lang AE, Strafella AP. Cerebral blood flow changes induced by pedunculopontine nucleus stimulation in patients with advanced Parkinson’s disease: A 15O H2O PET study. Human Brain Mapping 2009; 30: 3901-3909.
148. Barr MS, Farzan F, Rusjan PM, Chen R, Fitzgerald PB, Daskalakis ZJ. Potentiation of gamma oscillatory activity through repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex. Neuropsychopharmacology 2009; 34: 2357-2367.
149. Udupa K, Ni Z, Gunraj C, Chen R. Interactions between short latency afferent inhibition and long interval intracortical inhibition. Experimental Brain Research 2009; 199: 177-183.
150. Obhi SS, Matkovich S, Chen R. Changing the “when” and “what” of intended actions. Journal of Neurophysiology 2009;102: 2755-2762.
151. Wagle-Shukla A, Ni Z, Gunraj CA, Bahl N, Chen R. Effects of short interval intracortical inhibition and intracortical facilitation on short interval intracortical facilitation in human primary motor cortex. Journal of Physiology 2009; 587: 5565-5678.
152. Ni Z, Anastakis DJ, Gunraj C, Chen R. Reversal of cortical reorganization in human primary motor cortex following thumb reconstruction. Journal of Neurophysiology 2010; 103: 65-73.
153. Kuriakose R, Saha U, Castillo G, Udupa K, Ni Z, Gunraj C, Mazzella F, Hamani C, Lang AE, Moro E, Lozano AM, Hodaie M, Chen R. The nature and time course of cortical activation following subthalamic stimulation in Parkinson’s disease. Cerebral Cortex 2010; 20:1926-1936.
154. Farzan F, Barr MS, Levinson AJ, Wong W, Chen R, Fitzgerald PB, Daskalakis ZJ. Evidence for gamma inhibition deficits in the dorsolateral prefrontal cortex of patients with schizophrenia. Brain 2010; 133: 1505-1514.
155. Chen R. Transcranial direct current stimulation as a treatment for Parkinson’s disease – interesting, but not ready for prime time. Journal of Neurology, Neurosurgery and Psychiatry 2010;81: 1061.
156. Nelson AJ, Hoque T, Gunraj CA, Ni Z, Chen R. Impaired interhemispheric inhibition in writer’s cramp. Neurology 2010;75: 441-447.
157. Tsang E, Hamani C, Moro E, Mazzella F, Poon Y-Y, Andres Lozano AM, Chen R. Involvement of the human pedunculopontine nucleus region in voluntary movements. Neurology 2010;75: 950-959.
158. Yeh I-J, Tsang EW, Hamani C, Moro E, Mazzella M, Poon Y-Y, Lozano AM, Chen R. Somatosensory evoked potentials recorded from the human pedunculopontine nucleus region. Movement Disorders 2010;25:2076-2083.
159. Kirton A, deVeber G, Gunraj C, Chen R. Cortical excitability and interhemispheric inhibition after subcortical pediatric stroke: Plastic organization and effects of rTMS. Clinical Neurophysiology 2010; 121:1922-1929.
160. Torres CV, Moro E, Lopez-Rios A-L, Hodaie M, Chen R, Laxton AW, Hutchison WD, Dostrovsky JO, Lozano AM. Deep brain stimulation of the ventral intermediate nucleus of the thalamus for tremor in patients with multiple sclerosis. Neurosurgery 2010; 67: 646-651.
161. Chen R. Repetitive transcranial magnetic stimulation as treatment for depression in Parkinson’s disease. Movement Disorders 2010;25: 2272-2273.
162. Barr MS, Farzan F, Tran LC, Chen R, Fitzgerald PB, Daskalakis ZJ. Evidence for excessive frontal evoked gamma oscillatory activity in schizophrenia during working memory. Schizophrenia Research 2010;121: 146-52.
163. Udupa K, Zhen N, Gunraj C, Chen R. Effect of long interval inter hemispheric inhibition on intra cortical inhibitory and facilitatory circuits. Journal of Physiology 2010;588: 2633-2641.
164. Sanger TD, Chen D, Fehlings DL, Hallett M, Lang AE, Mink JW, Singer HS, Alter K, Ben-Pazi H, Butler EE, Chen R, Collins A, Dayanidhi S, Forssberg H, Fowler E, Gilbert DL, Gorman SL, Gormley ME Jr, Jinnah HA, Kornblau B, Krosschell KJ, Lehman RK, Mackinnon C, Malanga CJ, Mesterman R, Michaels MB, Pearson TS, Rose J, Russman BS, Sternad D, Swoboda KJ, Valero-Cuevas F. Definition and classification of hyperkinetic movements in childhood. Movement Disorders 2010;25: 1538-1549.
165. Farzan F, Barr MS, Levinson AJ, Chen R, Wong W, Fitzgerald PB, Daskalakis ZJ. Reliability of long interval cortical inhibition in healthy human subjects: A TMS-EEG study. Journal of Neurophysiology 2010;104: 1339-1346.
166. Voineskos AN, Farzan F, Barr MS, Lobaugh NJ, Mulsant BH, Chen R, Fitzgerald PB, Daskalakis ZJ. The role of the corpus callosum in TMS-induced interhemispheric signal propagation. Biological Psychiatry 2010;68: 825-831.
167. Lim SY, Poon YY, Chen R, Mikulis D, Lozano AM, Moro E. Marked reduction of tremor in essential tremor after putaminal infarct. Journal of Neurology Neurosurgery and Psychiatry 2010;81:1172-3.
168. Ni Z, Pinto AD, Lang AE, Chen R. Involvement of the cerebellothalamocortical pathway in Parkinson’s disease. Annals of Neurology2010, 68:816-824.
169. Rajji TK, Liu S-K, Frantseva MV, Mulsant BH, Thoma J, Chen R, Fitzgerald PB, Daskalakis ZJ. Exploring the effect of inducing long-term potentiation in the human motor cortex on motor learning. Brain Stimulation 2011; 4: 137-144.
170. Ni Z, Charab S, Gunraj C, Nelson AJ, Udupa K, Yeh I-J, Chen R. Transcranial magnetic stimulation in different current directions activates separate cortical circuits. Journal of Neurophysiology 2011; 105: 749-756.
171. Espay AJ, Chen R. Primary writing tremor and writer’s cramp: distinct phenomenology, diverging pathophysiology. Clinical Neurophysiology 2011; 122: 5-6 (Editorial).
172. Ni Z, Chen R. Excitatory and inhibitory effects of transcranial magnetic stimulation. Biocybernetics and Biomedical Engineering 2011; 31: 93–105.
173. Chen R, Brashear A. A diagnostic test to distinguish psychogenic dystonia from organic dystonia? Neurology 2011; 76: 590-591 (Editorial).
174. Ni Z, Müller-Dahlhaus F, Chen R, Ziemann U. Triple-pulse transcranial magnetic stimulation to study interactions between neural circuits in human cortex. Brain Stimulation 2011; 4: 281-293.
175. Heldman DA, Giuffrida JP, Chen R, Payne M, Mazzella F, Duker AP, Sahay A, Kim SJ, Revilla FJ, Espay AJ. The modified bradykinesia rating scale for Parkinson’s disease: Reliability and comparison with kinematic measures. Movement Disorders 2011, 26: 1859-1863.
176. Zadikoff C, Wadia PM, Miyasaki J, Chen R, Lang AE, So J, Fox SH. Cannabinoid, CB1 agonists in cervical dystonia: Failure in a phase IIa randomized controlled trial. Basal Ganglia 2011; 1: 91-95.
177. Jog M, Chouinard S, Hobson D, Grimes D, Chen R, Bhogal M, Simonyi S. Causes for treatment delays in dystonia and hemifacial spasm: A Canadian survey. Canadian Journal of Neurological Sciences 2011, 38: 704-711.
178. Ni Z, Gunraj C, Wagle-Shukla A, Udupa K, Mazzella F, Lozano AM, Chen R. Direct demonstration of inhibitory interactions between long interval intracortical inhibition and short interval intracortical inhibition. Journal of Physiology 2011;589: 2955-2962.
179. Tsang EW, Hamani C, Moro E, Mazzella F, Lozano AM, Hodaie M, Yeh I-J,Chen R. Movement-related potentials and oscillatory activities in the human internal globus pallidus during voluntary movements. Journal of Neurology, Neurosurgery and Psychiatry2012; 83: 91-97.
180. Barr MS, Farzan F, Arenovich T, Chen R, Fitzgerald PB, Daskalakis ZJ. The effect of repetitive transcranial magnetic stimulation on gamma oscillatory activity in schizophrenia. Public Library of Science One(PLoS One) 2011; 6: e22627.
181. Moro E, Schwalb JM, Piboolnurak P, Poon YY, Hamani C, Hung SW, Arenovich T, Lang AE, Chen R, Lozano AM. Unilateral subdural motor cortex stimulation improves essential tremor but not Parkinson’s disease. Brain 2011; 134: 2096-2105.
182. Armstrong MJ, Shah BB, Chen R, Angel MJ, Lang AE. Expanding the phenomenology of benign hereditary chorea: Evolution from chorea to myoclonus and dystonia. Movement Disorders 2011, 26: 2296-2297.
183. Espay AJ, Giuffrida, JP, Chen R, Payne M, Mazzella F, Dunn E, Vaughan JE, Duker AP, Sahay A, Kim SJ, Revilla FJ, Heldman DA. Differential response of speed, amplitude, and rhythm to dopaminergic medications in Parkinson’s disease. Movement Disorders 2011, 26:2504-2508.
184. Nelson AJ, Premji A, Rai N, Hoque T, Tommerdahl T, Chen R. Dopamine alters tactile perception in Parkinson’s disease. Canadian Journal of Neurological Sciences 2012, 39:52-57.
185. Chen R. Repetitive transcranial magnetic stimulation as a treatment for essential tremor? Clinical Neurophysiology 2012, 123:850-851 (Editorial).
186. Zamir O, Gunraj C, Ni Z, Mazzella F, Chen R. Effects of theta burst stimulation on motor cortex excitability in Parkinson’s disease. Clinical Neurophysiology 2012, 123:815-821.
187. Tsang E, Hamani C, Moro E, Mazzella F, Lozano AM, Yeh I-J, Chen R. Prominent 5-18 Hz oscillations in the pallidal-thalamic circuit in secondary dystonia. Neurology 2012, 78:361-363.
188. Chen R. Paradoxical worsening of gait with levodopa in Parkinson disease. Neurology 2012, 78:446-447 (Editorial).
189. Tsang E, Hamani C, Moro E, Mazzella F, Saha U, Lozano AM, Hodaie M, Chuang R, Steeves TDL, Lim S-Y, Neagu B, Chen R. Subthalamic deep brain stimulation at individualized frequencies for Parkinson disease. Neurology 2012, 78:1930-1938.
190. Blumberger DM, Christensen BK, Zipursky RB, Moller B, Chen R, Fitzgerald PB, Daskalakis ZJ. MRI-targeted repetitive transcranial magnetic stimulation of Heschl’s gyrus for refractory auditory hallucinations. Brain Stimulation 2012, 5:577-585.
191. Elahi B, Gunraj C, Chen R. Short-interval intracortical inhibition blocks long-term potentiation induced by paired associative stimulation. Journal of Neurophysiology 2012, 107:1935-1941.
192. Elahi, B, Phielipp N, Chen R. N-Methyl-D-Aspartate antagonists in levodopa induced dyskinesia: A meta-analysis. Canadian Journal of Neurological Sciences 2012, 39: 465-472.
193. Mestre T, AE Lang, JJ Ferreira, Almeida V, Carvalho M, Miyasaki M, Chen R, Fox SH. Associated movement disorders in orthostatic tremor: a case series. Journal of Neurology, Neurosurgery and Psychiatry2012, 83: 725-729.
194. Miyasaki JM, Long J, Mancini D, Moro E, Fox SH, Lang AE, Marras C, Chen R, Strafella A, Arshinoff R, Ghoche R, Hui J. Palliative care for advanced Parkinson disease: An interdisciplinary clinic and new scale, the ESAS-PD. Parkinsonism and Related Disorders 2012, Suppl 3, S6-9.
195. Chen R. How can we solve the debate on the nature of CRPS, fixed dystonia and peripheral trauma-induced movement disorders? Basal Ganglia 2012, 2: 237-239.
196. Márquez-Chin C, Popovic M, Sanin E, Chen R, Lozano AM. Real-time two dimensional control of a computer cursor with a single subdural electrode. The Journal of Spinal Cord Medicine 2012, 35: 382-391.
197.Golestanirad L, Rouhani H, Elahi B, Shahim K, Chen R, Mosig JR, Pollo C, Graham S. Combined use of transcranial magnetic stimulation and metal electrode implants: A theoretical assessment of safety considerations. Physics in Medicine and Biology 2012, 57: 7813-7827.
198. Li J-Y, Lai P-H, Chen R. Transcallosal inhibition in patients with callosal infarction. Journal of Neurophysiology 2013,109: 659-665.
199. Ni Z, Bahl N, Gunraj CA, Mazzella M, Chen R. Increased motor cortical facilitation and decreased inhibition in Parkinson’s disease. Neurology 2013, 80: 1746-1753.
200. Chen R. Biomarker for mild cognitive impairment: Is short latency afferent inhibition the answer? Movement Disorders 2013, 28: 1171-1172.
201. VanLoh M, Chen R, Kluger B. Safety of transcranial magnetic stimulation in Parkinson’s disease: A review of the literature. Parkinsonism and Related Disorders 2013, 19: 573-585.
202. Yugeta A, Hutchison WD, Hamani C, Saha U, Lozano AM, Hodaie M, Moro E, Neagu B, Chen R. Modulation of beta oscillations in the subthalamic nucleus with prosaccades and antisaccades in Parkinson’s disease. The Journal of Neuroscience 2013, 33: 6895-6904.
203. Ghosh S, Mehta AR, Huang G, Gunraj C, Hoque T, Saha U, Ni Z, Chen R. Short and long-latency inter-hemispheric inhibition are additive in the human motor cortex. Journal of Neurophysiology 2013, 109: 2955-2962.
204. Wagle Shukla A, Moro E, Gunraj C, Poon Y-Y, Lozano AM, Hodaie M, Lang AE, Chen R. Long-term subthalamic nucleus stimulation improves sensorimotor integration and proprioception. Journal of Neurology, Neurosurgery and Psychiatry 2013, 84: 1020-1028.
205. Chen R. Message from the new Editor-in-Chief. Canadian Journal of Neurological Sciences 2013, 40:453.
206. Barry MD, Bunday KL, Chen R, Perez MA. Selective effects of baclofen on use-dependent modulation of GABAB inhibition after tetraplegia. The Journal of Neuroscience 2013, 33: 12898-12907.
207. Farzan F, Barr MS, Hoppenbrouwers SS, Fitzgerald PB, Chen R, Pascual-Leone A, Daskalakis ZJ. The EEG correlates of the TMS induced EMG silent period. Neuroimage 2013, 83: 120-134.
208. Udupa K, Chen R. Motor cortical plasticity in Parkinson’s disease. Frontiers in Neurology 2013, 4:128. doi: 10.3389/fneur.2013.00128.
209. Neagu B, Tsang E, Mazzella M, Hamani C, Moro E, Hodaie M, Lozano AM, Chen R. Pedunculopontine nucleus evoked potentials from subthalamic nucleus stimulation in Parkinson’s disease. Experimental Neurology 2013, 250: 221-227.
210. Golestanirad L, Elahi B, Molina A, Mosig JR, Pollo C, Chen R, Graham S. Analysis of fractal electrodes for efficient neural stimulation. Frontiers in Neuroengineering 2013,6:3. doi: 10.3389/fneng.2013.00003
211. de Jesus DR, Favalli G, Hoppenbrouwers SS, Barr, MS, Chen R, Fitzgerald PB, Daskalakis ZJ.Determining optimal rTMS parameters through changes in cortical inhibition. Clinical Neurophysiology 2014,125: 755-762.
212. Christopher L, Marras C, Duff-Canning S, Koshimori Y, Chen R, Boileau I, Segura B, Lang AE, Rusjan P, Houle S, Strafella AP. Combined insular and striatal dopamine dysfunction are associated with executive deficits in Parkinson’s Disease with mild cognitive impairment. Brain 2014, 137: 565-575.
213. Elahi B, Hutchison WD, Daskalakis ZJ, Gunraj C, Chen R. Dose response curve of associative plasticity in human motor cortex and interactions with motor learning. Journal of Neurophysiology 2014, 111: 594-601.
214. Udupa K, Ni Z, Gunraj C, Chen R. Effects of short latency afferent inhibition on short interval intracortical inhibition. Journal of Neurophysiology 2014, 111: 1360-1361.
215. Kashigar A, Udupa K, Fish J, Chen R. Neurophysiological assessment of fatigue in electrical injury patients. Experimental Brain Research 2014, 232: 1013-1023.
216. Udupa K, Chen R. Theta burst stimulation to explore the sensory-motor integration of cortical circuits. Clinical Neurophysiology 2014, 125: 2146.
217. Ni Z, Gunraj C, Kailey P, Cash RF, Chen R. Heterosynaptic modulation of motor cortical plasticity in human. The Journal of Neuroscience 2014, 34:7314-7321.
218. Vesia M, Chen R. Focal hand dystonia: using brain stimulation to probe network interactions and guide brain plasticity. Movement Disorders 2014, 29: 1227-1229.
219. Bronstein JM, Tagliati M, McIntyre C, Chen R, Cheung T, Hargreaves EL, Israel Z, Moffitt M, Montgomery EB, Stypulkowski P, Shils J, Denison T, Vitek J, Volkman J, Wertheimer J, Okun M. The rationale driving the evolution of DBS to constant current devices. Neuromodulation 2015, 18: 85-88.
220.Li J-Y, Chen R. Increased intracortical inhibition in hyperglycemic hemichorea-hemiballism. Movement Disorders2015, 30: 198-205.
221. Ni Z, Isayama R, Castillo G, Gunraj C, Saha U, Chen R. Reduced dorsal premotor cortex and primary motor cortex connectivity in older adults. Neurobiology of Aging 2015, 36: 301-303.
222. Radhu N, Garcia Dominguez L, Farzan F, Richter MA, Semeralul M, Chen R, Fitzgerald PB, Daskalakis ZJ. Evidence for inhibitory deficits in the prefrontal cortex in schizophrenia. Brain 2015, 138: 483-497.
223. Christopher L, Duff-Canning S, Koshimori Y, Segura B, Boileau I, Chen R, Lang A, Houle S, Rusjan P, Strafella, A. Salience network and parahippocampal dopamine dysfunction in memory impaired Parkinson’s Disease. Annals of Neurology 2015, 77: 269-280.
224. Chen R. A year of change and further changes ahead. Canadian Journal of Neurological Sciences 2015, 42: 1.
225. Cash RFH, Isayama R, Gunraj CA, Ni Z, Chen R. The influence of sensory afferent input on local motor cortical excitatory circuitry in human. Journal of Physiology 2015, 593 1667-1684.
226. Shah BB, Chen R, Zurowski M, Kalia LV, Gunraj C, Lang AE. Repetitive transcranial magnetic stimulation plus standardized suggestion of benefit for functional movement disorders: An open label case series. Parkinsonism & Related Disorders 2015, 21: 407-412.
227. ZanjaniA, Zakzanis KK, Daskalakis ZJ, Chen R. Repetitive transcranial magnetic stimulation of the primary motor cortex in the treatment of motor signs in Parkinson’s disease: A quantitative review of the literature. Movement Disorders 2015, 30: 750-758.
228. Rossini PM, Burke D, Chen R, Cohen LG, Daskalakis Z, Di Iorio R, Di Lazzaro V, Ferreri F, Fitzgerald PB, George MS, M. Hallett, Lefaucheur JP, Langguth B, Matsumoto H, Miniussi C, Nitsche MA, Pascual-Leone A, Paulus W, Rossi S, Rothwell JC, Siebner HR, Ugawa Y, Walsh V, Ziemann U. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee. Clinical Neurophysiology 2015, 126: 1071-1107.
229. Pirio Richardson S, Tinaz S, Chen R. Repetitive transcranial magnetic stimulation in cervical dystonia: effect of site and repetition in a randomized pilot trial. PLoSOne 2015,10(4):e0124937.
230. Kim SJ, Udupa K, Ni Z, Moro E, Gunraj C, Mazzella F, Lozano AM, Hodaie M, Lang AE, Chen R. Effects of subthalamic nucleus stimulation on motor cortex plasticity in Parkinson disease. Neurology 2015, 85: 425-432.
231. Udupa K, Ghahremani A, Chen R. Are we close to the advent of closed loop deep brain stimulation in Parkinson’s disease? Movement Disorders 2015, 30: 1326.
232. Udupa K, Chen R. The mechanisms of action of deep brain stimulation and ideas for the future development. Progress in Neurobiology 2015, 133: 27-49.
235. Ni Z, Chen R. Transcranial magnetic stimulation to understand pathophysiology and as potential treatment for neurodegenerative diseases. Translational Neurodegeneration 2015, 4:22.
234. Udupa K, Chen R. Role of dopamine in motor cortex plasticity in Parkinson’s disease. Movement Disorders 2016, 31: 43.
235. Cash RFH, Murakami T, Chen R, Thickbroom GW, Ziemann U. Augmenting plasticity-induction in human motor cortex by disinhibition stimulation (DIS). Cerebral Cortex 2016, 26: 59-69.
236. Udupa K, Bahl N, Zhen Ni, Gunraj C, Mazzella F, Moro E, Hodaie M, Lozano A, Lang AE, Chen R. Cortical plasticity induction by pairing subthalamic nucleus deep brain stimulation and primary motor cortical transcranial magnetic stimulation in Parkinson’s disease. The Journal of Neuroscience 2016, 36: 369-404.
227. Ganos C, Maugest L, Apartis E, Gasca-Salas C, Cáceres-Redondo MT, Erro R, Navalpotro I, Batla A, Elena Antelmi E, Degos B, Roze E, Welter M-L, Mestre T, Palomar FJ, Isayama R, Chen R, Cordivari C, Mir P, Lang AE, Fox SH, Bhatia KP, Vidailhet M. The long-term outcome of orthostatic tremor. Journal of Neurology, Neurosurgery and Psychiatry 2016, 87: 167-172.
238. Bridgman AC, Barr MS, Goodman MS, Chen R, Rajji TK, Daskalakis ZJ, George TP. Deficits in GABAA receptor function and working memory in non-smokers with schizophrenia. Schizophrenia Research 2016, 171: 152-130.
239. Brys M, Fox, MD, Agarwal S, Biagioni M, Dacpano G, Kumar P, Pirraglia E, Chen R, Wu, A, Fernandez H, Wagle-Shukla A, Lou J-S,GrayZ, Simon DK, Di Rocco A, MD1, Pascual-Leone, A. Multifocal Repetitive TMS for Motor and Mood Symptoms of Parkinson’s Disease: a Randomized Trial. Neurology 2016, 87 1907-1915.
239. Levy, A, Chen R. Myoclonus: Pathophysiology and treatment options. Current Treatments in Neurology 2016, 13: 21.
240. Udupa K, Chen R. Deeper understanding of the role of dopamine in reward, learning and motivation. Movement Disorders 2016, 31: 498.
241. Noda Y, Cash RF, Zomorrodi R, Garcia Dominguez L, Farzan F, Rajji TK, Barr MS, Chen R, Daskalakis ZJ, Blumberger DM. A combined TMS-EEG study of short-latency afferent inhibition in the motor and dorsolateral prefrontal cortex. Journal of Neurophysiology 2016, 116: 938-948.
242. Wessel JR, Ghahremani, A, Udupa K, Saha U, Kalia SK, Hodaie M, Lozano, AM, Aron AR, Chen R. Stop-related subthalamic beta activity indexes global motor suppression in Parkinson’s Disease. Movement Disorders2016, 31: 1846-1853.
243. Brown MJN, Antonella Macerollo, Kilner JM, Chen R. Is closed-loop time-locked M1 stimulation ideal for improving movements in neurological disorders? Movement Disorders 2016, 31: 1341.
244. Goldenberg NM, Steinberg BE, Rutka JT, Chen R, Cabral V, Rosenblum N, Kapus A, Lee WL.A growing chasm – declining participation of resident physicians in basic science research. CMAJ open 2016, 4: E444-E447.
245. Bridgman AC, Barr MS, Goodman MS, Zomorrodi R, Rajji T, Le Foll B, Chen R, Daskalakis ZJ, George TP. Effects of varenicline on motor cortical plasticity in non-smokers with schizophrenia. Schizophrenia Research 2016, 178: 50-55.
246. Talakoub O, Neagu B, Udupa K, Tsang E, Chen R, Popovic M, Wong W. Time-course of coherence in the human basal ganglia during voluntary movements. Scientific Reports 2016, 6: 34930.
247. Wilson JR, BSc LT, Aarabi B, Anderson PA, Arnold PM, Brodke DS, Burns A, Chen R, Chiba K, Dettori J, Furlan JC, Harrop JS, Holly LT, Jeji T, Kalsi-Ryan S, Kotter M, Kurpad SN, Kwon BK, Marino R, Martin AR, Massicotte EM, Merli G, Middleton J, Nakashima H, Nagoshi N, Palmieri K, Shamji MF, Singh A, Skelly A, Yee A, Fehlings M. Guidelines for the management of patients with spinal cord injury: the optimal timing of decompression. Neurosurgery 2016, 63 Suppl 1:172.
248. Cash RF, Noda Y, Zomorrodi R, Radhu N, Farzan F, Rajji T, Fitzgerald P, Chen R, Daskalakis ZJ, Blumberger D. Characterisation of glutamatergic and GABAA mediated neurotransmission in motor and dorsolateral prefrontal cortex using paired-pulse TMS-EEG. Neuropsychopharmacology 2017:42-502.
249. Cash RFH, Jegatheeswaran G, Ni Z, Chen R. Modulation of the direction and magnitude of Hebbian plasticity in human motor cortex by stimulus intensity and concurrent inhibition. Brain Stimulation 2017, 10: 83-90 12.
250. Weissbach A, Bäumer T, Pramstaller PP, Brüggemann N, Tadic V, Chen R, Klein C, Münchau A. Abnormal premotor-motor interaction in heterozygous Parkin- and PINK1 mutation carriers. Clinical Neurophysiology 2017, 128: 275-280
251. Phielipp M, Saha U, Sankar T, Yugeta A, Chen R. Safety of repetitive transcranial magnetic stimulation in patients with implanted subdural cortical electrodes. An ex-vivo study and report of a case. Clinical Neurophysiology 2017,128: 1109-1115.
252. Radhu N, Garcia Dominguez L, Greenwood TA, Farzan F, Semeralul MO, Richter MA, Kennedy JL, Blumberger DM, Chen R, Fitzgerald PB, Daskalakis ZJ. Investigating cortical inhibition in first-degree relatives and probands in schizophrenia. Scientific Report 2017, 7:43629.
253. Yoshida T, Masani K, Zabjek K, Chen R, Popovic MR. Dynamic cortical participation during bilateral, cyclical ankle movements: effects of aging. Scientific Report 2017;7:44658.
254. Noda Y, Zomorrodi R, Cash RF, Barr MS, Farzan F, Rajji TK, Chen R, Daskalakis ZJ, Blumberger DM. Characterization of the influence of age on GABAA and glutamatergic mediated functions in dorsolateral prefrontal cortex using paired-pulse TMS-EEG. Aging 2017; 9: 556-572.
255. Cash RF, Dar A, Hui J, De Ruiter L, Baarbé J, Fettes P, Peters S, Fitzgerald PB, Downar J, Chen R. Influence of inter-train interval on the plastic effects of rTMS. Brain Stimulation 2017 10: 630-636.
256. Pirio Richardson S, Altenmüller E, Alter K, Alterman RL, Chen R, Frucht S, Furuya S, Jankovic J, Jinnah HA, Kimberley TJ, Lungu C, Perlmutter JS, Prudente CN and Hallett M. Research priorities in limb and task-specific dystonias. Frontiers in Neurology 2017; 8:170.
257. Yoshida T, Masani K, Zabjek K, Chen R, Popovic MR. Dynamic increase in corticomuscular coherence during bilateral, cyclical ankle movements. Frontiers in Human Neuroscience 2017;11:155.
258. Turco CV, El-Sayes J, Fassett HJ, Chen R, Nelson AJ. Modulation of long-latency afferent inhibition by the amplitude of sensory afferent volley. Journal of Neurophysiology 2017: 118: 610-618.
259. Vesia M, Barnett-Cowan M, Elahi B, Jegatheeswaran G, Isayama G, Neva JL, Davare M, Staines WR, Culham JC, Chen R. Human dorsomedial parieto-motor circuit specifies grasp during the planning of goal-directed hand actions. Cortex 2017, 92: 175-186.
260. Noda Y, Zomorrodi R, Backhouse F, Cash RFH, Barr MS, Rajji TK, Chen R, Daskalakis ZJ, Blumberger DM. Reduced prefrontal short-latency afferent inhibition in older adults and its relation to executive function: A TMS-EEG study. Frontiers in Aging Neuroscience, 2017; 9: 119.
261. Antal A, Alekseichuk I, Bikson M, Brockmöller J, Brunoni AR, Chen R, Cohen LG, Dowthwaite G, Ellrich J, Flöel A, Fregni F, George MS, Hamilton R, Haueisen J, Herrmann CS, Hummel FC, Lefaucheur JP, Liebetanz D, Loo CK, McCaig CD, Miniussi C, Miranda PC, Moliadze V, Nitsche MA, Nowak R, Padberg F, Pascual-Leone A, Poppendieck W, Priori A, Rossi S, Rossini PM, Rothwell J, Rueger MA, Ruffini G, Schellhorn K, Siebner HR, Ugawa Y, Wexler A, Ziemann U, Hallett M, Paulus W. Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. Clinical Neurophysiology 2017, 128: 1774-1809.
262. Rastogi A, Cash R, Dunlop K, Vesia M, Kucyi A, Ghahremani A, Downer J, Chen J, Chen R. Modulation of cognitive cerebro-cerebellar functional connectivity by lateral continuous cerebellar theta burst stimulation. Neuroimage 2017, 158: 48-57.
263. Ghahremani A, Chen R. Deep brain stimulation modulates the shape of cortical beta oscillations in Parkinson’s disease. Movement Disorders 2017, 32: 1377.
264. Suppa A, Quartarone A, Siebner H, Chen R, Di Lazzaro V, Del Giudice P, Paulus W, Rothwell JC, Ziemann U, Classen J. The associative brain at work: Evidence from paired associative stimulation studies in humans. Clinical Neurophysiology 2017, 128: 2140-2164.
265. Hallett M, Di Iorio R, Rossini PM, Park JE, Chen R, Celnik P, Strafella AP, Matsumoto H, Ugawa Y. Contribution of transcranial magnetic stimulation to assessment of brain connectivity and networks. Clinical Neurophysiology 2017, 128: 2125-2139.
266. Noda Y, Barr MS, Zomorrodi R, Cash FHR, Farzan F, Rajji TK, Chen R, Daskalakis ZJ, Blumberger DM. Evaluation of short interval cortical inhibition and intracortical facilitation from the dorsolateral prefrontal cortex in patients with schizophrenia. Scientific Reports 2017, 7: 17106.
267. Noda Y, Barr MS, Zomorrodi R, Cash RFH, Rajji TK, Farzan F, Chen R, George TP, Daskalakis ZJ, Blumberger DM. Reduced short-latency afferent inhibition in prefrontal but not motor cortex and its association with executive function in schizophrenia: a combined TMS–EEG study. Schizophrenia Bulletin 2018, 44: 193-202.
268. Salavati B, Rajji TK, Zomorrodi R, Blumberger DM, Chen R, Pollock BG, Daskalakis ZJ. Pharmacological manipulation of cortical inhibition in the dorsolateral prefrontal cortex. Neuropsychopharmacology 2018, 43: 354-361.
269. Freedman M, Binns M, Gao F, Holmes M, Roseborough A, Strother S, Vallesi A, Jeffers S, Alain C, Whitehouse P,11 Ryan J, Chen R, Cusimano M, Black S. Mind-matter interactions and the frontal lobes of the brain: A novel neurobiological model of psi inhibition. Explore 2018, 14: 76-85.
270. Espay AJ, Maloney T, Vannest J, Norris MM, Eliassen JC, Neefus E, Allendorfer JB, Chen R, Szaflarski JP. Dysfunction in emotion processing underlies functional (psychogenic) dystonia. Movement Disorders 2018, 33: 136-145.
271. Wennberg R, Steriade C, Chen R Andrade D. Frontal infraslow activity marks the motor spasms of anti-LGI1 encephalitis. Clinical Neurophysiology 2018, 129: 59-68.
272. Ghahremani A, Wessel JR, Udupa K, Neagu B, Zhuang P, Saha U, Kalia SK, Hodaie M, Lozano AM, Aron AR, Chen R. Stopping and slowing manual and spoken responses: similar oscillatory signatures recorded from the subthalamic nucleus. Brain and Language 2018, 176: 1-10.
273. Buard I, Sciacca DM, Martin CS, Rogers S, Sillau SH, Chen R, Kluger BM. Transcranial magnetic stimulation does not improve mild cognitive impairment in Parkinson’s disease. Movement Disorders 2018, 33: 489-491.
274. Chen R. Spatial versus temporal inhibition in dystonia. Clinical Neurophysiology 2018, 129: 458-459.
275. Wagle Shukla A, Ostrem JL, Vaillancourt DE, Chen R, Foote, KD, Okun M. Physiological effects of subthalamic nucleus deep brain stimulation surgery in cervical dystonia. Journal of Neurology, Neurosurgery and Psychiatry 2018, 89: 1296-1300.
276. Ni Z, Kim SJ, Phielipp N, Ghosh S, Udupa K, Gunraj C, Saha, U, Hodaie M, Kalia S, Lozano A, Lee D, Moro E, Fasano A, Hallett, M, Lang A, Chen R. Pallidal deep brain stimulation modulates cortical excitability and plasticity. Annals of Neurology 2018, 83: 352-362.
277. Macerollo A, Brown MJN, Kilner JM, Chen R. Neurophysiological changes measured using somatosensory evoked potentials. Trends in Neuroscience 2018, 41: 298-310.
278. Salavati B, Daskalakis ZJ, Zomorrodi R, Blumberger D, Chen R, Pollock B, Rajji T. Pharmacological modulation of long-term potentiation-like activity in the dorsolateral prefrontal cortex. Frontiers in Human Neuroscience 2018, 12: 155.
279.Yoshida T, Masani K, Zabjek L, Popovic MR, Chen R. Dynamic cortical participation during bilateral, cyclical ankle movements: Effects of Parkinson’s disease. PlosOne 2018, 13: e0196177.
280. Boulias C, Ismail F, Phadke CP, Bagg S, Bureau I, Charest S, Chen R, Cheng A, Ethans K, Fink M, Finlayson H, Gulasingam S, Guo M, Haziza M, Hosseini H, Khan O, Lang M, Lapp T, Leckey R, Shan RLP, Liem N, Lo A, Mason M, McNeil S, McVeigh S, Miller T, Mills PD, Naud P, O’Connell C, Petitclerc M, Prevost J, Reebye R, Richardson D, Satkunam L, Sharma S, Short C, Sirois G, Unarket M, Wein T, Wilkins K, Winston P. A Delphi-based consensus statement on the management of anticoagulated patients with botulinum toxin for limb spasticity. Archives of Physical Medicine and Rehabilitation 2018, 99: 2183-2189.
281. Nelson AJ, Hoque T, Gunraj C, Chen R. Altered somatosensory processing in Parkinson’s disease and modulation by dopaminergic medications. Parkinsonism and Related Disorders 2018, 53: 76-81.
282. Jegatheeswaran G, Vesia M, Isayama R, Gunraj C, Chen R. Increases in motor cortical excitability during mirror visual feedback of a precision grasp is influenced by vision and movement of the opposite limb. Neuroscience Letters 2018, 681: 31-36.
283. Burke MJ, Isayama R, Jegatheeswaran G, Gunraj C, Feinstein A, Lang AE, Chen R. Neurostimulation for functional neurological disorder: Evaluating longitudinal neurophysiology. Movement Disorders Clinical Practice 2018, 5: 561-563.
284. McGregor HR, Vesia M, Rinchon C, Chen R, Gribble PL. Changes in corticospinal excitability associated with motor learning by observing. Experimental Brain Research 2018, 236: 2829-2838.
285. Vesia M, Culham JC, Jegatheeswaran G, Isayama R, Le A, Davare M, Chen R. Functional interaction between human dorsal premotor cortex and ipsilateral primary motor cortex for grasp plans: a dual-site TMS study. Neuroreport 2018, 29:1355-1359.
286. Ghahremani A, Aron AR, Udupa K, Saha U, Reddy D, Hutchison WD, Kalia SK Hodaie M, Lozano AM, Chen R. Event-related deep brain stimulation of the subthalamic nucleus affects conflict processing. Annals of Neurology 2018, 84: 515-526.
287. De Vloo P, Dallapiazza RF, Lee DJ, Zurowski M, Peng PW, Chen R, Hodaie M. Long-term relief of intractable hiccups with vagal nerve stimulation. Brain Stimulation 2018, 11: 1385-1387.
288. Ni Z, Cash RHF, Gunraj C, Bercovici E, Hallett M, Chen R. Involvement of different neuronal components in the induction of cortical plasticity with associative stimulation. Brain Stimulation 2019, 12: 84-86.
289. Turco CV, El-Sayes J, Locke MB, Chen R, Baker S, Nelson AJ. Effects of lorazepam and baclofen on short- and long-latency afferent inhibition. Journal of Physiology 2018, 596: 5267-5280.
290. Boutet A, Ileana H, Saha U, Crawley A, Xu D, Ranjan M, Hlasny E, Chen R, Foltz W, Sammartino F, Coblentz A, Kucharczyk W, Lozano AM. 3 Tesla MR imaging of deep brain stimulation patients: Safety assessment of coils and pulse sequences. Journal of Neurosurgery, published online February 22, 2019.
291. Ni Z, Udupa K, Hallett M, Chen R. Effects of deep brain stimulation on the primary motor cortex: Insights from transcranial magnetic stimulation studies. Clinical Neurophysiology 2019, 130: 558-567.
292. Harmsen IE, Lee DJ, Dallapiazza RF, De Vloo P, Chen R, Fasano A, Kalia SK, Hodaie M, Lozano AM. Ultra-high frequency deep brain stimulation at 10,000 Hz improves motor function. Movement Disorders 2019, 34: 146-148.
293. Isayama R, Vesia M, Jegatheeswaran G, Elahi B, Gunraj CA, Cardinali L, Farnè A, Chen R. Rubber hand illusion modulates the influences of somatosensory and parietal inputs to the motor cortex. Journal of Neurophysiology 2019, 121: 567-573.
294. Isayama R, Chen R, Lang AE, Deuschl G, Fasano A. Tremor with congenital mirror movements: Evidence of involvement of primary motor cortex in tremor. European Journal of Neurology 2019, 26: e66-e67.
295. Tremblay S, Rogasch NC, Premoli I, Blumberger DM, Casarotto S, Chen R, Di Lazzaro V, Farzan F, Ferrarelli F, Fitzgerald P, Hui J, Ilmoniemi R, Kimiskidis VK, Kugiumtzis D, Lioumis P, Pascual-Leone A, Pellicciari MC, Rajji T, Thut G, Zomorrodi R, Ziemann U, Daskalakis ZJ. Clinical utility and prospective of TMS-EEG. Clinical Neurophysiology 2019, 130: 802-844.
296. Vesia M, Pellicciari R, Cash RFH, Isayama R, Kunaratnam N, Jegatheeswaran G, Chen R. Learning from goal and action based observations differentially modulates functional motor cortical plasticity. Neuroscience 2019, 404: 387-395.
297. Valli M, Cho SS, Masellis M, Chen R, Rusjan P, Kim J, Koshimori Y, Mihaescu A, Strafella AP. DRD2 genotype-based variants modulates D2 receptor distribution in ventral striatum. Molecular Neurobiology 2019, 56: 6512-6520.
298. Brown MJN, Weissbach A, Pauly MG, Vesia M, Gunraj C, Baarbé J, Münchau A, Bäumer T, Chen R. Somatosensory-motor cortex interactions measured using dual-site transcranial magnetic stimulation. Brain Stimulation 2019, 12: 1229-1243.
299. Chen KS, Chen R. Invasive and non-invasive brain stimulation in Parkinson’s disease: Clinical effects and future perspectives. Clinical Pharmacology & Therapeutics 2019, 106: 736-775.
300. Rajalingam R, Breen DP, Chen R, Fox S, Kalia L, Marras C, Munhoz RP, Slow E, Strafella AP, Lang AE, Fasano A. The clinical significance of lower limb tremors. Parkinsonism and Related Disorders 2019, 65: 165-171.
301. Lizarraga KJ, Baarbé JK, Saravanamuttu J, Lang AE, Chen R. Cortical GABAergic dysfunction underlying abnormal hand movements in ARX mutation. Clinical Neurophysiology 2019, 130: 1750-1751.
302. Hui J, Zomorrodi R, Lioumis P, Salavati B, Rajji T, Chen R, Blumberger D, Daskalakis ZJ. Pharmacological Mechanisms of Interhemispheric Signal Propagation: a TMS-EEG study. Neuropsychopharmacology, published online July 29, 2019.
303. Brown MJN, Goldenkoff ER, Chen R, Gunraj C, Vesia M. Using dual-site transcranial magnetic stimulation to probe connectivity between the dorsolateral prefrontal cortex and ipsilateral primary motor cortex in humans. Brain Sciences 2019, 9: 177.
304. Weissbach A, Udupa K, Ni Z, Gunraj C, Rinchon C, Baarbe J, Fasano A, Munhoz RP, Lang A, Tadic V, Brüggemann N, Münchau A, Bäumer T, Chen R. Single-pulse subthalamic deep brain stimulation reduces premotor-motor facilitation in Parkinson’s disease. Parkinsonism and Related Disorders 2019, 66: 224-227.
305. Chen KS, Chen R. Principles of electrophysiological assessment for movement disorders. Journal of Movement Disorder 2019, in press.
306. Lizarraga KJ, Saravanamuttu J; Baarbé JK, Lang AE, Chen R. Interhemispheric pathways in agenesis of the corpus callosum and Parkinson’s disease. Brain Stimulation, published online Nov 4, 2019.
307. Chen R. Guideline on therapeutic use of repetitive transcranial magnetic stimulation: Useful but know the methods and limitations. Clinical Neurophysiology, published online December 31, 2019.
308. Beudel M, Macerollo A, Brown MJN, Chen R. The Role of the Basal Ganglia in Somatosensory-Motor Interactions: Evidence from Neurophysiology and Behavior. Frontiers in Human Neuroscience 2020, 13:451.
Books and Monographs
1. Bolton CF, Chen R, Wijdicks EFM, Zifko U. The Neurology of Breathing. Butterworth Heinemann, 2003.
2. Espay A, Chen R. Speed and amplitude of movement in patients with Parkinson’s disease. Lambert Academic Publishing, 2009
3. Chen, R, Rothwell JC (Eds). Assessing and modulating cortical connectivity and functions with cortical stimulation. Springer-Verlag, Berlin,2012.
4. Tsang EW, Chen R. Oscillatory activity of the basal ganglia in Parkinson’s disease and dystonia. Lambert Academic Publishing, 2014.
Book Chapters
1. Chen R, Young GB (1996). Metabolic encephalopathies. In Critical Care (Baillère’s Clinical Neurology, Vol 5, no. 3), edited by CF Bolton and GB Young. London: Baillère Tindall, pp. 577-598.
2. Zifko U, Chen R (1996). The respiratory system. In Critical Care (Baillère’s Clinical Neurology, Vol 5, no. 3), edited by CF Bolton and GB Young. London: Baillère Tindall, pp. 477-495.
3. Chen R, Hallett M (1998). Focal dystonia and repetitive motion disorders. In Clinical Orthopaedics and Related Research, number 351, edited by Richard J. Mandel and Donald F. Leatherwood II., pp.102-106.
4. Cohen LG, Ziemann U, ChenR (1999). Mechanisms, functional relevance and modulation of plasticity in the human central nervous system.Transcranial Magnetic Stimulation (EEG Suppl. 51). Editors: W Paulus, M Hallett, PM Rossini, JC Rothwell, pp 174-182.
5. Hallett M, Chen R, Ziemann U, Cohen LG (1999). Reorganization in motor cortex in amputees and in normal volunteers after ischemic limb deafferentation.Transcranial Magnetic Stimulation (EEG Suppl. 51). Editors: W Paulus, M Hallett, PM Rossini, JC Rothwell, pp 183-187.
6. Chen R (2002). Anatomy and physiology of respiration.In Clinical Neurophysiology and Neuromuscular Diseases.Edited by William F Brown, Charles F Bolton and Michael J Aminoff, W.B. Saunders Company, Philadelphia, pp. 567-575.
7. Chen R (2002). Effects of deep brain stimulation for treatment of Parkinson’s disease. In Advances in Clinical Neurophysiology, Supplements to Clinical Neurophysiology, Vol. 54. Edited by Ricardo C. Reisin, Marc R. Nuwer, Mark Hallett and Carlos C. Medina, pp. 410-415.
8. Angel M, Davey M, Ellaway P, Chen R (2003). Lesions of cord, root and peripheral nerve. In Plasticity in the Human Nervous System: Investigations with Transcranial Magnetic Stimulation. Edited by Simon Boniface and Ulf Ziemann, Cambridge University Press, Cambridge, pp. 204-230.
9. Daskalakis ZJ, Chen R (2005). The physiology and safety of repetitive transcranial magnetic stimulation (rTMS).In Magnetic Stimulation in Clinical Neurophysiology, 2nd Edition. Edited by Mark Hallett and Sudhansu Chokroverty, Elsevier, Philadelphia, pp. 61-81.
10. Pringsheim T, Chen R, Lang A (2005). Psychogenic motor disorders. In Higher Order Motor Disorders.Edited by Hans-Joachim Freund, Marc Jeannerod, Mark Hallett, Ramon Leiguarda, Oxford University Press, Inc., New York, pp.397-411.
11. Pal PK, Chen, R (2005). Electrophysiologic evaluation of movement disorders: An overview. In Parkinson’s Disease and Movement Disorders. Edited by TN Mehrotra, KB Bhattachary. Jaypee Brothers Medical Publishers (P) Ltd., New Delhi, pp 146-158.
12. Chen R, Curra A (2004). Measures of cortical inhibition in health and disease. In Advances in Clinical Neurophysiology, Supplements to Clinical Neurophysiology, Vol. 57. Edited by Mark Hallett, Lawrence H. Philips II, D.L. Schomer, Janice M. Massey, pp 691-701.
13.Anastakis D, Chen R, Davis D, Mikulis D (2005). Cortical plasticity following Upper Extremity Injury and Reconstruction. In Clinics in Plastic Surgery, Volume 32, No. 4.Edited by Nancy McKee.Elsevier, Philadelphia, pp 617-634.
14. Chen R, Cohen LG, Hallett M (2005). Nervous system reorganization following injury. In Pathophysiology: An Essential Text for the Allied Health Professions. Edited by DelvaShamley.Elsevier, p 325.
15. Hanajima R, Chen R, Ashby P, Lozano AM, Hutchison WD, Davis KD, Dostrovsky JO (2006). In Functional Neuroscience: Evoked Potentials and Related Techniques (Supplements to Clinical Neurophysiology, Vol. 59). Edited by C. Barber, S. Tsuji, S. Tobimatsu, T. Uozumi, N. Akamatsu, A. Eisen. Elsevier B.V., pp 119-124.
16. Hung SW-S, Molnar GF, Ashby P, Chen R, Voon V, Lang AE (2006). Eletrophysiologic testing in psychogenic tremor. Does it always help? In Psychogenic Movement Disorders, Edited by Mark Hallett, Stanley Fahn, Joseph Jankovic, Anthony E. Lang, C. Robert Cloninger, Stuart C. Yudofsky. Lippincott, Williams & Wilkins, Philadelphia.
17. Espay AJ, Chen R, Lang AE (2006).Psychogenic Torticollis. In Spasmodic Torticollis : Clinical Aspects and Treatment. Edited by Guy Bouvier, François de Soultrait and Pedro Molina-Negro, Expressions Santé, Paris, pp 81-90.
18. Daskalakis ZJ, Chen R (2008).Evaluating the Interaction between Cortical Inhibitory and Excitatory Circuits measured by Transcranial Magnetic Stimulation (TMS). In Oxford Handbook of Transcranial Magnetic Stimulation, Oxford University Press, Oxford, pp 119-133.
19. Angel MA, Chen R, Young GB (2008). Metabolic Encephalopathies.Volume Editors G. Bryan Young and Eelco F.M. Wijdicks, Series Editors Michael J. Aminoff, Francois Boller and Dick F. Swaab. In Disorders of Consciousness, Handbook of Clinical Neurology, 3rd series, Volume 90, Elsevier, Amsterdam, pp 115-166.
18. Espay AJ, Chen R (2008). Changing tremor in a 45-year-old woman.In Movement Disorders: 100 Instructive Cases. Edited by Stephen G. Riech. Taylor & Francis, London, pp 369-372.
19. Ni Z, Chen R (2009). Electrophysiological and pharmacological mechanisms of TMS and rTMS.In Repetitive transcranial magnetic stimulation in the treatment and rehabilitation of central nervous diseases.Edited by JuditMally.Eurobridge Co, Budapest, pp 9-22.
20. Udupa K, Chen R (2010) Single pulse transcranial magnetic stimulation. In Encyclopedia of Movement Disorders, Edited by Katie Kompoliti and Leonard VerhagenMetman, Elsevier.
21. Udupa K, Chen R (2010). Paired pulse transcranial magnetic stimulation. In Encyclopedia of Movement Disorders, Edited by Katie Kompoliti and Leonard VerhagenMetman, Elsevier.
22. Udupa K, Chen R (2010). Repetitive transcranial magnetic stimulation.In Encyclopedia of Movement Disorders, Edited by Katie Kompoliti and Leonard VerhagenMetman, Elsevier.
23. Steeves T, Chen R (2010). Motor control of movement disorders.In MedLink Neurology.
24. Chen R, Berardelli, A (2011). Physiology of psychogenic dystonia.In Psychogenic Movement Disorders and Other Conversion Disorders. Edited by Mark Hallett, Anthony E. Lang, Joseph Jankovic, Stanley Fahn, Peter W. Halligan, Valerie Voon, C. Robert Cloninger. Cambridge University Press, Cambridge, pp 205-208.
25. Petrescu N, Chen R (2011). Diagnostic and therapeutic role of magnetic stimulation in Neurology.In Aminoff’sEletrodiagnosis in Clinical Neurology, 6th Edition.Edited by Michael J. Aminoff. Elsevier Saunders, pp 615-631.
26. Phielipp N, Chen R (2012). Motor control of movement disorders.In MedLink Neurology.
27. Ni Z, Chen R (2012). Intracortical interaction and their interactions in the primary motor cortex.In Cortical Connectivity.Edited by Robert Chen and John C. Rothwell, Springer-Verlag, Berlin, pp 49-69.
28. Ni Z, Chen R (2012). Changes in cortical circuits in movement disorders.In Cortical Connectivity.Edited by Robert Chen and John C. Rothwell, Springer-Verlag, Berlin, pp 253-277.
29. Espay AJ, Chen R (2013). Myoclonus: Clinical features, pathophysiology, and treatment. In Continnum, Movement Disorders Issue.Edited by Alberto J. Espay, American Academy of Neurology.
30. Udupa K, Chen R (2013). Central motor conduction time. In Handbookof Clinical Neurology 2013;116:375-86
31. Pal PK, Chen R (2014). Breathing and the nervous system. In Aminoff’s General Medicine and Neurology, 5th Edition. Edited by Michael J. Aminoff and S. Andrew Josephson. Elsevier, Amsterdam, pp 3-23.
32. Philippe N, Chen R (2014). Neurophysiologic assessment of movement disorders in human. In Movement Disorders, 2nd Edition. Edited by Mark S. Ledoux. Elsevier, Amsterdam, pp171-186.
33. Phielipp N, Chen R (2015). Motor control of movement disorders (updated). In MedLink Neurology.
34. Udupa, K, Chen, R (2017). Paired Pulse TMS. In Reference Module in Neuroscience and Biobehavioral Psychology, Elsevier, 2017.
35. Phielipp N, Chen R (2017). Motor control of movement disorders (updated). In MedLink Neurology.
36. Phielipp N, Chen R (2019). Motor control of movement disorders (updated). In MedLink Neurology.
37. Udupa K, Chen R (2019). Motor cortical circuits in Parkinson’s disease and dystonia. In Neurophysiology: Diseases and Disorders, Handbook of Clinical Neurology, Volume 161, 3rd series. Edited by Kerry H. Levin, Patrick Chauvel, Elsevier, San Diego, pp.167-186
Letters
1. Dargis V, Chen R, Brown D, Viberti GC, Keen H, Walker J. Urine collection from disposable nappies.Lancet 1991, 338: 1077-1078.
2. Wassermann EM, Cohen LG, Flitman SS, Chen R, Hallett M. Seizures in healthy people with repeated “safe” trains of transcranial magnetic stimuli. Lancet 1996, 347: 825.
3. Chen R, Bolton CF. Phrenic nerve conduction study. Muscle and Nerve 1996, 19: 1057-1058.
4. Espay AJ, Chen R, Moro E, Lang AE. Fixed dystonia unresponsive to pallidal stimulation improved by motor cortex stimulation. Neurology 2007,69:1062-1063.
5. Lang AE, Angel M, Bhatia K, Chen R, Fahn S, Hallett M, Schrag A, Thompson P. Myoclonus in complex regional pain syndrome. Movement Disorders 2009, 24:314-316.
6. Lang AE, Chen R. Dystonia in complex regional syndrome type I. Annals of Neurology 2010, 67:412-414.
7. Lang AE, Prashanth LK, Ghosh S, Elahi B, Chen R. Extreme task specificity: Is it dystonia or another form of motor programming abnormality? Movement Disorders 2012, 27: 1302-1303. 2012.
8. van Gerpen JA, Ahlskog JE, Chen R, Fung VS, Hallett M. Orthostatic myoclonus associated with Caspr2 antibodies. Neurology 2016, 87:1187-1188.
9. Ni Z, Hallett M, Chen R. Reply to “Corticopallidal connectivity: Lessons from patients with dystonia”. Annals of Neurology 2018 84: 159.
10. Tipton PW, van Gerpen JA, Chen R. Video NeuroImages: Paraneoplastic spinal myoclonus associated with Caspr2 antibodies. Neurology 2019 92:302-304.
INVITED LECTURES AND PRESENTATIONS
1. Results of somatosensory evoked potentials in anoxic-ischemic encephalopathy. Presentation in Special Interest Group of Evoked Potentials/Critical Care, American Association of Electrodiagnostic Medicine Annual Meeting, San Francisco, California, October 1994.
2. Investigating polyneuropathies. Presentation at Congress course “Electrophysiological studies in the Critical Care Unit”, 31st Meeting of the Canadian Congress of Neurological Sciences, London, Ontario, June 26, 1996.
3. Involvement of ipsilateral motor cortex in finger movements of different complexities. Francis McNaughton Memorial Prize Lecture, 31st Meeting of the Canadian Congress of Neurological Sciences, London, Ontario, June 27, 1996.
4. The time course of corticospinal excitability following reaction time and self-paced movements. Herbert Jasper Prize Lecture, 33rd Meeting of the Canadian Congress of Neurological Sciences, Montreal, Quebec, June 20, 1998.
5. Botulinum toxin type F: Long term experience. Presentation at Chemodenervation Special Interest Group meeting, American Association of Electrodiagnostic Medicine Annual Meeting, Orlando, Florida, October 17, 1998.
6.Parkinson’s disease: new approaches to treatment. Presentation at Issues in Geriatric Medicine Clinical Day, Baycrest Centre for Geriatrics, Toronto, November 27, 1998
7. Unusual Neuropathies. Presentation at Zwestern nerve conduction focus course and workshop, The Toronto Hospital, Toronto, January 24, 1999.
8. Plasticity of the human motor system following peripheral injury. Neuroscience Seminar, Queen’s University, Kingston, Ontario, November 22, 2000.
9. Applications of magnetic brain stimulation. Neurology Rounds, Queen’s University, Kingston, Ontario, November 23, 2000.
10. Magnetic brain stimulation. Schizophrenia Seminar, Center of Addiction and Mental Health, University of Toronto, Toronto, Ontario, December 1, 2000
11. Update on Magnetic Stimulation of the Brain, Advances in Medicine 2001 Conference, Hong Kong Convention and Exhibition Center, Hong Kong, April 7, 2001.
12. Effects of deep brain stimulation for the treatment of Parkinson’s disease. Symposium on Magnetic Stimulation, XV International Congress of Clinical Neurophysiology, Buenos Aires, Argentina, May 16, 2001.
13. Changing Cortical Excitability with Magnetic Stimulation: Potential applications to Pain. Wasser Pain Management Centre Rounds, Mount Sinai Hospital, Toronto, November 28, 2001.
14. Studies of cortical functions with transcranial magnetic stimulation. Neurology Grand Rounds, Robert Wood Johnson Medical School, New Jersey, January 16, 2002.
15. Dystonia: Clinical features, etiology and evaluation. Presentation at Treatment of Dystonia: Workshop demonstrating the use of botulinum toxin, organized by the American Academy of Neurology and Movement Disorders Society, Washington DC, February 22, 2002.
16. Brain changes in response to peripheral injury. Neuromuscular Section Academic Session, University of Toronto, Toronto, Ontario, October 9, 2002
17. Anatomy and physiology of the respiratory system. Critical Care Special Interest Group meeting, American Association of Electrodiagnostic Medicine Annual Meeting, Toronto, Ontario, October 10, 2002.
18. Magnetic stimulation in movement disorders. Presented at the 7th International Congress of Parkinson’s Disease and Movement Disorders, Miami, Florida, November 13, 2002.
19. Physiology: Transcranial magnetic stimulation. Presented at the meeting of NIH task force on childhood motor disorder, Palo Alto, California, January 26, 2003.
20. The thalamocortical pathway in essential tremor. Presented at the Transcranial Magnetic Stimulation in Movement Disorders meeting, Santa Margherita Ligure, Italy, March 15, 2003
21. The Basal Ganglia, Deep Brain Stimulation and Motor System Plasticity. Presented at Neuroscience Rounds, Krembil Neuroscience Centre, Toronto Western Hospital, University Health Network, Toronto, Ontario, May 22, 2003
22. Interaction between different inhibitory systems in the human motor cortex. Presented at International transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) Symposium, 29th Gottingen Neurobiology Conference, Gottingen, Germany, June 12, 2003.
23. Plasticity: Theoretical aspects and clinical evidence. Presented at 57th annual meeting of the American Academy of Cerebral Palsy and Developmental Medicine, Montreal, Quebec, September 13, 2003.
24. Measures of cortical inhibition in health and disease. Presented at the join scientific meeting of the 50th Anniversary of the American Association of Electrodiagnostic Medicine, the 27th International Congress of Clinical Neurophysiology and 57th Annual Meeting of the American Clinical Neurophysiology Society, San Francisco, California, September 20, 2003.
25. How does stroke recovery occur? Medical Grand Rounds, Toronto Western Hospital, University Health Network. Toronto, Ontario, October 8, 2003
26. Neurophysiology of the respiratory system. University of Toronto Neuromuscular Academy Day, Toronto, Ontario, October 17, 2003
27. Long-latency reflex and transcranial magnetic stimulation. Presented at the meeting of NIH task force on childhood motor disorder, Dallas, Texas, February 28, 2004.
28. Killam Lecture – The functions and connections of the basal ganglia: Insights from deep brain stimulation. Presented at the Montreal Neurological Institute, Montreal, Quebec, March 23, 2004
29. Plasticity of the motor system in response to peripheral injury. Presented at the Society of Biological Psychiatry’s 59th Annual Scientific Program and Convention, New York City, New York, April 29, 2004
30. Measures of cortical inhibition in health and disease. Presented at the 4th International Satellite Symposium on New Developments in Clinical Neurophysiology, Samsun, Turkey, May 27, 2004.
31. Contributions of transcranial magnetic stimulation to the evaluation of extrapyramidal system function. Presented at the 4th International Satellite Symposium on New Developments in Clinical Neurophysiology, Samsun, Turkey, May 27, 2004.
32. Magnetic stimulation in movement disorders. Presented at the 8th International Congress of Parkinson’s Disease and Movement Disorders, Rome, Italy, June 15, 2004.
33. Transcranial magnetic stimulation and cortical plasticity. Presented at Cortical Plasticity Panel, Meeting of the Sunderland Society, Toronto, Ontario, September 15, 2004.
34. Cortical representation of facial muscles in human. Presented at University of Toronto Neuromuscular Academic Day, Toronto, Ontario, October 26, 2004.
35. Functions of the basal ganglia: Insights from deep brain stimulation. Presented at Medical Grand Rounds, Toronto General Hospital, Toronto, Ontario, January 20, 2005.
36. How TMS works and insights it provides into movement disorders. Presented at the 9th International Congress of Parkinson’s disease and Movement Disorders, New Orleans, Louisiana, March 6, 2005.
37. Electrophysiological study of movement disorder patients. Presented at the 9th International Congress of Parkinson’s disease and Movement Disorders, New Orleans, Louisiana, March 7, 2005.
38. Transcranial magnetic stimulation: An investigational and treatment tool in neurology and psychiatry. Presented at Research Seminar, Queen’s University, Kingston, Ontario, Canada, May 11, 2005.
39. Electrophysiological assessment of movement disorders. Presented at Neurology seminar, DokuzEylul University Medical School, Izmir, Turkey, May 17, 2005.
40. Transcranial magnetic stimulation and movement disorders. Presented at the 6th Turkish Congress of Parkinson’s Disease and Movement Disorders, Cesme, Turkey, May 19, 2005.
41. Physiological assessment of movement disorders. Presented at Neurologic Clinic seminar, University of Wuerzburg, Wuerzburg, Germany, June 10, 2005.
42. The motor functions and connections of the basal ganglia: Insights from deep brain stimulation. Presented at the Centre for Neuroscience Seminar, University of Alberta, Edmonton, Alberta, Canada, June 21, 2005.
43. Transcranial magnetic stimulation: An investigational and treatment tool in neurology and psychiatry. Presented at Research Seminar, University of Alberta, Edmonton, Alberta, Canada, June 29, 2005.
44. Plasticity of the human motor system following peripheral nervous system injury. Presented at Neuroscience Rounds, University of Alberta, Edmonton, Alberta, Canada, September 2, 2005.
45. The motor functions and connections of the basal ganglia: Insights from deep brain stimulation (Keynote speech). Presented at the 10th Annual Conference of theInternational Functional Electrical Stimulation Society, Montreal, Quebec, Canada, July 6, 2005.
46. Cortical projection to facial muscles: an intracranial stimulation study. Presented at University of Toronto Neuromuscular Academic Day, Toronto, Ontario, November 5, 2005
47. Hyperkinetic movement disorders. Presented at Neuroscience Rounds, Sunnybrook & Women’s College Hospital, Toronto, Ontario, January 5, 2006.
48. Functional anatomy and localization techniques. Presented at Canadian botulinum toxin conference 2006, Toronto, Ontario, January 28, 2006.
49. Mechanism of deep brain stimulation: inhibition or excitation? (Keynote speech) Presented at the 3rd Annual meeting of the Italian Deep Brain Stimulation Group, Taormina, Italy, March 17, 2006.
50. The motor functions and connections of the basal ganglia. Presented at Neuroscience seminar, University of Toronto at Scarborough, Toronto, Ontario, March 29, 2006.
51. The physiological effects and mechanisms of deep brain stimulation. Presented at Applied and Interventional Research meeting, Toronto Western Research Institute, Toronto, Ontario, April 27, 2006.
52. Measurement and modulation of brain plasticity with TMS. Presented at the meeting of the Association for Convulsive Therapy and the International Society for Transcranial Stimulation, Toronto, Ontario, May 21, 2006.
53. Hyperkinetic disorders: Pathophysiology and treatment. Presented at Psychiatry Grand Rounds, St. Joseph’s Healthcare, Hamilton, Ontario, June 8, 2006.
54. The physiological effects and mechanisms of deep brain stimulation. Presented at the Institute of Movement Neuroscience seminar, Queen Square and University College, London, United Kingdom, July 7, 2006.
55. Clinical utility of TMS. Presented at 28th International Congress of Clinical Neurophysiology, Edinburgh, United Kingdom, September 11, 2006
56. TMS: Intracortical inhibition (workshop). Presented at 28th International Congress of Clinical Neurophysiology, Edinburgh, United Kingdom, September 11, 2006.
57. Psychogenic movement disorders and weakness. The neurophysiology of movement and its disorder (symposium). Presented at 28th International Congress of Clinical Neurophysiology, Edinburgh, United Kingdom, September 14, 2006.
58. Physiology of psychogenic movement disorders and weakness. Presented at the University of Toronto Neuromuscular Day, Toronto, Ontario, October 20, 2006
59. Skills Workshop: Neurophysiological evaluation of complex movement disorders. Presented at the 10th International Congress of Parkinson’s Disease and Movement Disorders, Kyoto, Japan, October 30, 2006
60. The physiological effects and mechanism of deep brain stimulation. Presented at Neuroscience symposium, Tokushima University, Tokushima, Japan, November 2, 2006
61. Physiology of psychogenic movement disorders. Presented at Neuropsychiatry Rounds, Toronto Western Hospital, University Health Network, November 30, 2006.
62. Adult and pediatric spasticity and dystonia. Presented at “How to treat neurological disease with botulinum toxin workshop”, American Academy of Neurology Winter Meeting, Orlando, Florida, January 12, 2007.
63. Magnetic Stimulation of the Central Nervous System. Presented at Recent Advances in Transcranial Magnetic Stimulation Conference, Niagara-on-the-Lake, Ontario, March 3, 2007.
66. Diagnostic challenges: What are the clinical clues? Presented at Spine Course: Movement Disorder and the Myelopathic patient, 42 Annual Congress of the Canadian Neurological Sciences Federation, Edmonton, Alberta, June 20, 2007.
67. Local field potentials in movement planning. Presented at the Dana Foundation Cognitive Neurophysiology Consortium Meeting, Direct Recordings from the Human Brain, University of California Los Angeles, June 23, 2007.
68. Cortical inhibition and facilitation in psychiatric and neurological disorders. Presented at the 4th Annual Joint EEG Clinical Neuroscience Society and the International Society for Neuroimaging in Psychiatry Conference, Montreal, Quebec, September 20, 2007.
69. Sensory deficits in dystonia: Psychophysics, imaging and TMS studies. Presented at the Dystonia Imaging Workshop, Dystonia Medical Research Foundation, Washington DC, October 10, 2007
70. Measurement and modulation of brain plasticity in humans using transcranial magnetic stimulation. Presented at the symposium: “Neurorehabilitation from Physiology to Physical Therapy”, Meeting of the Canadian Physiological Society, Lake Louise, Alberta, January 24, 2008.
71. Limits of stimulation parameters for “rhythmic” rTMS: the “guideline” table. Presented at the Present and future of TMS.Safety and Ethical Guidelines Meeting, Siena, Italy, March 8, 2008.
72. Role of magnetic stimulation in motor disorders. Presented at the Annual University of Toronto Neuromuscular Day, Toronto, Ontario, March 28, 2008.
73. Measurement and modulation of brain plasticity in humans using transcranial magnetic stimulation. Presented at Department of Anesthesia Rounds, University of California San Diego, May 7, 2008.
74. Basal ganglia recordings and mechanisms of deep brain stimulation. Presented at Symposium on Mechanisms of Neuromodulation: How electromagnetic stimulation can change nervous system function, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, May 23, 2008.
75. Transcranial magnetic stimulation. Presented at the 2nd Annual Meeting of the Canadian Neuromodulation Society, Banff, Alberta, May 24, 2008.
76. Transcranial magnetic stimulation studies in movement disorders. Presented at the Annual Meeting of the North American Society for the Psychology of Sports and Physical Activity, Niagara Falls, Ontario, June 8, 2008
77. Theta burst stimulation and other transcranial magnetic stimulation approaches in motor behavior. Presented at Transcranial Magnetic Stimulation and NeuroImaging in Cognition and Behavior meeting, University of Montreal, Montreal, Quebec, September 24, 2008
78. Are SICI, or other paired pulse intracortical paradigms useful investigative tools in movement disorders? Presented at the Third International Conference on Transcranial Magnetic and Direct Current Stimulation, University of Göttingen, Göttingen, Germany, October 3, 2008.
79. Transcranial magnetic stimulation: Basic principles and applications. Presented at Neurotology rounds, Division of Otolaryngology, University of Toronto, November 26, 2008.
80. Diagnosis and treatment of tremor and dystonia. Lecture to Northern Ontario Medical School (via videolink), February 10, 2009.
81. Botulinum toxin: When, why and what can go wrong? Presented at the Annual University of Toronto Muscular Day, Toronto, Ontario, March 27, 2009
82. Pathophysiology of psychogenic dystonia. Presented at 2nd International Conference on Psychogenic Movement Disorders and Other Conversion Disorders, Washington DC, April 10, 2009.
83. Transcranial magnetic stimulation: Excitation and inhibition. Presented at symposium Brain stimulation: Superficial and deep, old and new, International Centre of Biocybernetics: Polish Academy of Sciences, Warsaw, Poland, May 11, 2009.
84. Deep brain recordings. Presented at symposium Brain stimulation: Superficial and deep, old and new, International Centre of Biocybernetics: Polish Academy of Sciences, Warsaw, Poland, May 12, 2009
85. Electrophysiological evaluation of patients with movement disorders. Presented at the 13th International Congress of Parkinson’s Disease and Movement Disorders, Paris, France, June 10, 2009.
87. Transcranial magnetic stimulation in dystonia and chorea. Presented at the meeting of the Task Force on Childhood Motor Disorders: Hyperkinetic Symptoms in Childhood, Dallas, Texas, July 12, 2009.
88. Role of the basal ganglia in voluntary movement and mechanisms of deep brain stimulation. Presented at Centre for Neuroscience Seminar, University of Alberta, Edmonton, Alberta, August 27, 2009
89. Basal ganglia physiology and deep brain stimulation. Presented at Workshop on Deep Brain Stimulation, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Minneapolis, MN, September 2, 2009.
90. Physiology of the basal ganglia and the pedunculopontine nucleus. Presented at Neurology seminar, West Virginia University, Morgantown, WV, September 30, 2009.
91. Cortical inhibition and facilitation. Presented at Seminar in Neuroscience, West Virginia University, Morgantown, WV, September 30, 2009.
92. Stiff-person syndrome. Presented at Etobicoke General Hospital Neurology Rounds, November 20, 2009.
93. Expert case review of writer’s cramp and tremor. Presented at the 4th Canadian Botulinum Toxin Conference, Newport Beach, CA, January 30, 2010.
94. Anatomy of the upper limb. Presented at the 4th Canadian Botulinum Toxin Conference, Newport Beach, CA, January 30, 2010.
95. Clinical usefulness of botulinum toxin and treatment of dystonia. Demonstrated at the 62nd Meeting of the American Academy of Neurology, Toronto, Ontario, April 16, 2010
96. Cortical changes following amputation and functional restoration. Presented the Annual University of Toronto Neuromuscular Day, Toronto, Ontario, April 23, 2010.
97. Heterotopic plasticity: Paired associative stimulation. Presented at the First Workshop on Synaptic Plasticity: from Bench to Bedside, Giardini-Naxos, Italy, April 29, 2010.
98. Interhemispheric inhibition in writer’s cramp. Presented at the First International Congress on Treatment of Dystonia, Hannover, Germany, May 7, 2010.
99. Repetitive transcranial magnetic stimulation: General principles and safety issues. Presented at Recent Advances in Brain Stimulation 2010 meeting, Montreal, Quebec, October 7, 2010.
100. Intracortical inhibition in movement disorders. Presented at the 29th International Congress of Clinical Neurophysiology, Kobe, Japan, October 29, 2010.
102. Repetitive transcranial magnetic stimulation: potential role in treatment of neurological disorders and safety issues. Presented the Annual University of Toronto Neuromuscular Day, Toronto, Ontario, March 25, 2011.
103. Repetitive magnetic stimulation of the brain: general principles and safety issues. Presented at the Fifth Annual Canadian Neuroscience Meeting, Quebec City, Quebec, May 30, 2011.
104. The neurophysiology of myoclonus: asking the right question. Presented at the 15th International Congress of Parkinson’s Disease and Movement Disorders, Toronto, Ontario, June 6, 2011.
105. Cortical inhibition, facilitation and plasticity in movement disorders. Presented at Panther Rehabilitation Grand Round, University of Pittsburg, Pittsburg, PA, July 20, 2011.
106. Physiology of tremors and myoclonus. Presented at Neuroscience Seminar, Singapore Neuroscience Institute, Singapore General Hospital Campus, Singapore, August 24, 2011
107. Cortical excitability and plasticity in Parkinson’s disease. Presented the Hong Kong Movement Disorder Society Quarterly Meeting, Queen Elizabeth Hospital, Hong Kong, August 30, 2011.
108. Measurement and modulation of plasticity of the motor systems in humans using transcranial magnetic stimulation. Presented at Departmental Seminar, Department of Rehabilitation Sciences, the Hong Kong Polytechnic University, Hong Kong, August 31, 2011.
109. Magistral Lecture: Neurophysiology of myoclonus. Presented at the 2nd Refresher Course in Movement Disorders: Chorea, myoclonus and therapy of Parkinson, Rubiera, Italy, September 17, 2011.
110. Transcranial magnetic stimulation: Clinical diagnostic, research and therapeutic applications. Presented at Neuroscience Round, Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada, September 20, 2011.
111. Role of the basal ganglia in voluntary movements and mechanisms of deep brain stimulation. Presented at Physics & Astronomy Colloquium, Departments ofApplied Mathematics and Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada, September 20, 2011.
112. Botulinum neurotoxin and deep brain stimulation (Workshop). Presented at the Toxins 2011, the 7th International Conference on Basic and Therapeutic aspects of Botulinum and Tetanus toxins, Santa Fe, MN, October 4, 2011.
113. Anatomy for the botulinum neurotoxin injector (Workshop). Presented at the Toxins 2011, the 7th International Conference on Basic and Therapeutic aspects of Botulinum and Tetanus toxins, Santa Fe, MN, October 5, 2011.
114. Physiology and pathophysiology of dystonia: Lessons from deep brain stimulation. Presented at the 5th International Dystonia Symposium, Barcelona, Spain, October 21, 2011.
115. Role of the basal ganglia in voluntary movement and mechanisms of deep brain stimulation. Presented at UCLA Brain Mapping Centre Seminar, Los Angeles, CA, January 5, 2012.
116. Can we use clinical neurophysiology to differentiate dystonia from chorea, ataxic movements, or other involuntary movements such as myoclonus or tremor? Presented at the Meeting on Childhood Motor Disorder, Diagnosis and Quantification, Bethesda, MD, February 3, 2012
117. Abnormal sensorimotor integration in dystonia and Parkinson’s disease. Presented at Neuroscience Seminar, INSERM, Lyon, France, February 7, 2012.
118. How can we solve the debate on nature of CRPS, fixed dystonia and peripheral trauma-induced movement disorder? Presented at 2nd International Congress on Knowledge Gaps in Parkinson’s Disease and Other Movement Disorders, Santa Margherita Ligure, Italy, February 10, 2012.
119. Investigative studies in focal dystonia: plasticity–what have we learned? Presented at Musician’s Summit, Dystonia Medical Research Foundation, New York, New York, March 9, 2012.
120. Transcranial magnetic stimulation and deep brain stimulation. Presented at Students for Technology and Engineering in Medicine (STEM) meeting, University of Toronto, March 28, 2012.
121. Research opportunities and developing an academic career in Canada. Presented at the Futures in Clinical Research Luncheon, the 64thAnnual Meeting of the American Academy of Neurology, New Orleans, Louisiana, April 23, 2012
122. Physiology of myoclonus and role of electrophysiological testing. Presented at Myoclonus Teaching Course, the 64thAnnual Meeting of the American Academy of Neurology, New Orleans, Louisiana, April 24, 2012
123. Overview of transcranial magnetic stimulation clinical research. Presented at the Symposium of TMS Treatment of Substance Addiction, National Institutes of Health, Bethesda, Maryland, April 30, 2012.
124. Interactions between different cortical circuits in the motor cortex. Presented at Magstim Neuroscience Conference, University of Oxford, Oxford, United Kingdom, May 12, 2012.
125. Role of the basal ganglia in voluntary movements and mechanisms of deep brain stimulation. Presented at Parkinson’s Disease Workshop, Focus Program on “Towards Mathematical Modeling of Neurological Disease from Cellular Prospective”, Fields Institute, University of Toronto, May 22, 2012.
126. Limb dystonia and spasticity. Presented at Comprehensive Neurotoxin Course for Neurological Disorders, Cleveland Clinic, May 30, 2012.
127. Using transcranial magnetic stimulation for neurological therapy. Presented at the Society for Brain Mapping and Therapeutic’sNinth Annual World Congress on Brain and Spinal Cord Mapping and Image Guided Therapy, Toronto, June 3, 2012
128. Role of the basal ganglia in voluntary movements and effects of deep brain stimulation. Presented at Neuroscience Seminar, Department of Neurology and Psychiatry, Sapienza, University of Rome, Rome, Italy, July 2, 2012.
129. Psychogenic dystonia: Diagnosis, pathophysiology, controversies. Presented at Medical Grand Round, University Health Network and Mt. Sinai Hospital, Toronto, October 3, 2012.
130. Role of the basal ganglia in voluntary movements and plasticity in Parkinson’s disease. Presented at Neuroscience and Neurology seminar, Eberhard Karls University of Tübingen, Tübingen, Germany, November 7, 2012.
131. Changes in the human basal ganglia with voluntary movements and effects of deep brain stimulation. Presented at Neurology Grand Round, Emory University, Atlanta, GA, January 11, 2013.
132. Non-invasive brain stimulation in Parkinson’s disease. Presented at the 5th International Conference on Non-invasive brain stimulation 2013, Leipzig, Germany, March 20, 2013.
133. Mechanisms of deep brain stimulation: Insights from transcranial magnetic stimulation. Presented at the 1st Taiwan International Congress of Parkinson’s Disease and Movement Disorders, Taipei, Taiwan, March 30, 2013.
134. Anatomy for botulinum toxin injectors. Presented at the 2nd International Congress on Treatment of Dystonia, Hannover, Germany, May 9, 2013.
135. Tremor. Presented at Movement Disorders and Parkinson’s Disease Review, 48th Annual Congress of the Canadian Neurological Sciences Federation, Montreal, Quebec, June 12, 2013.
136. Myoclonus. Presented at Movement Disorders and Parkinson’s Disease Review, 48th Annual Congress of the Canadian Neurological Sciences Federation, Montreal, Quebec, June 12, 2013.
137. Lessons learned from neurophysiology, in the Pathophysiology of Hyperkinetic Movement Disorders (Plenary Session). Presented at the 17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, Australia, June 18, 2013.
138. Mechanisms of action of deep brain stimulation in Parkinson’s Disease. Presented at Inter-hospital Neurology Grand Rounds, Sir Charles Gardiner Hospital, Perth, Australia, June 21, 2013.
139. Transcranial magnetic stimulation and movement disorders. Presented at the Australian Neuromuscular Research Institute seminar, Perth, Australia, June 21, 2013.
140. Role of the basal ganglia in voluntary movements and mechanisms of deep brain stimulation. Presented at Neuroscience Research Group seminar, Hong Kong Polytechnic University, Hong Kong, June 26, 2013.
141. Limb dystonia and spasticity. Presented at the 2nd Annual Comprehensive Neurotoxin Course for Neurological Conditions. Cleveland Clinic. October 9, 2013.
142. Using transcranial magnetic stimulation to investigate mechanisms of deep brain stimulation. Presented at the American Society of Neurorehabilitation Annual Meeting, San Diego, CA, November 7, 2013.
143. CIHR grant review. Presented at University of Toronto Third Annual Clinician Investigator Program Symposium, Toronto, November 27, 2013.
144. Research career and clinician scientist training program. Presented at Internal Medicine Interest Group, University of Toronto, Toronto, November 27, 2013.
145. Role of the human basal ganglia in voluntary movements and mechanisms of deep brain stimulation. Presented at University of Montreal Neuroscience Seminar, Montreal, Quebec, Canada, January 10, 2014.
146. Anatomy of upper and lower limbs. Presented at Canadian Botulinum Toxin Conference 2014, Montreal, Quebec, Canada, February 1, 2014.
147. Transcranial magnetic stimulation in Movement Disorders. Present at Department of Clinical Neuroscience Grand Rounds, University of Calgary, Calgary, Alberta, Canada, February 21, 2014.
148. Clinical diagnostic utility of transcranial magnetic stimulation. Presented at the 30th International Congress of Clinical Neurophysiology, Berlin, Germany, March 20, 2014.
149. Functional (psychogenic) movement disorders. Presented at the 30th International Congress of Clinical Neurophysiology, Berlin, Germany, March 21, 2014.
150. Role of transcranial magnetic stimulation in the management of movement disorders. Presented at the Plenary Session, the 6th Singapore International Parkinson’s Disease and Movement Disorders Symposium, April 4, 2014.
151. Electrophysiology studies in muscle jerks and spasms. Presented at the 6th Singapore International Parkinson’s Disease and Movement Disorders Symposium, April 4, 2014.
152. Transcranial magnetic stimulation in dystonia. Presented at the 6th Singapore International Parkinson’s Disease and Movement Disorders Symposium, April 4, 2014.
153. Mechanisms of deep brain stimulation in Parkinson’s disease: Insights from transcranial magnetic stimulation. Presented at NINDS Symposium, Human Motor Control: 30 years of Research at NIH and Beyond, National Institutes of Health, Bethesda, MD, April 24, 2014.
154. Functional axial jerks and myoclonus. Presented at Neurocritical Care Special Interest Group, 49th Congress of the Canadian Neurosciences Federation, Banff, Alberta, June 3, 2014.
155. Transcranial magnetic stimulation in Parkinson’s disease. Presented at the International Forum on Motor Control and Parkinson’s Disease, Beijing, China, September 2, 2014.
156. Research funding in Canada and grant review workshop (co-chair). Presented at the 26th meeting of the Parkinson Study Group, St. Louis, MO, September 19, 2014.
157. Transcranial magnetic stimulation in clinical research. Presented by Sunnybrook Canadian Partnership for Stroke Recovery Round, Toronto, Ontario, October 10, 2014.
158. Modulation of basal ganglia oscillations with voluntary movements. Presented at Mapping Normal Brain Function/Activity Symposium, the E. Harry Botterell Lectureship in Neurosurgery, Toronto, Ontario, November 10, 2014.
159. Perspectives on clinician scientist training. Presented at Department of Surgery Research Strategic Planning Meeting, Toronto, Ontario, January 23, 2015.
160. Current & Developing Non-therapeutic uses of Non-invasive brain stimulation: Overview Talk. Presented at Non-Invasive Neuromodulation of the Central Nervous System: A Workshop, Forum on Neuroscience and Nervous System Disorder, Institute of Medicine of the National Academies, Washington DC, March 2, 2015.
161. Transcranial magnetic stimulation in Parkinson’s disease. Presented at the 2nd Taiwan International Congress of Parkinson’s Disease and Movement Disorders, Taipei, Taiwan, March 29, 2015
162. Transcranial magnetic stimulation in Parkinson’s disease. Presented at the 3rd North America Meeting on Brain Stimulation and Neuroimaging, Montreal, Quebec, April 28, 2015
163. Focal dystonia management and new approaches. Presented at CNS Expert Meeting, Mexico City, Mexico, May 28, 2015.
164. Plasticity induction. Presented at International Symposium on Magnetic Stimulation: Past, Present and Future, Tokyo, Japan, June 6, 2015
165. Regular repetitive transcranial magnetic stimulation. Presented at International TMS Symposium in Fukushima, Fukushima, Japan, June 7, 2015
166. Myoclonus: Etiology, pathophysiology and treatment. Presented at the Therapeutic Plenary Session, 19th International Congress of Parkinson’s Disease and Movement Disorders, San Diego, June 14, 2015.
167. Homeostatic and non-homeostatic plasticity interactions. Presented at the 15th European Congress on Clinical Neurophysiology, Brno, Czech Republic, October 1, 2015.
168. Non-invasive brain stimulation to understand disease pathophysiology and advance treatment: Parkinson’s Disease. Presented at the 15th European Congress on Clinical Neurophysiology, Brno, Czech Republic, October 2, 2015.
169. MD/PhD Subspeciality Workshop. Presented at Canadian Society for Clinical Investigatin/Canadian Investigator Trainee Association Annual Meeting, Toronto, Ontario November 25, 2015.
170. Overview of transcranial magnetic stimulation and TMS technology. Presented at Introduction to Administering rTMS for Physicians, Temerty Centre for Therapeutic Brain Intervention, Toronto, Ontario, November 27, 2015
171. Clinical applications of TMS: Stroke, Parkinson’s Disease and other Movement Disorders. Presented at Introduction to Administering rTMS for Physicians, Temerty Centre for Therapeutic Brain Intervention, Toronto, Ontario, November 27, 2015
172. Parkinson’s Disease Research Directions. Presented at Neurodegenerative Disease Society of Toronto, University of Toronto, Toronto, Ontario, February 4, 2016
173. Dystonia pathogenesis: Plasticity. Presented at Dystonia Coalition’s 7th Meeting, Rockville, MD, March 3, 2016.
174. Basal ganglia oscillations and basal ganglia-cortical interactions. Presented at Toronto Computational Neuroscience Workshop, Toronto, Ontario, March 8, 2016.
175. Basal ganglia oscillations and basal ganglia-cortical interactions. Presented at Krembil Research Institute Research Seminar, Toronto, Ontario, June 17, 2016.
176. Novel neuromodulation strategies for Parkinson’s disease. Presented at the XXI Congress of the International Society of Electrophysiology and Kinesiology, Chicago, IL, July 6, 2016.
177. Modulation of cortical plasticity and excitatory-inhibitory balance. Presented at Special Seminar Series, the Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, August 29, 2016.
178. Special considerations for subjects with implants. Link to deep brain stimulation intensities and safety issues. Presented at Safety Conference on Transcranial Electrical Stimulation, Max Planck Institute for Experimental Medicine, Göttingen, Germany, September 6, 2016.
179. Basal-ganglia cortical interaction. Presented at 6th International Conference on
Transcranial Brain Stimulation, Göttingen, Germany, September 8, 2016.
180. How to help your movement disorders (MD) colleagues sort out organic and psychogenic MD in your EMG Lab. Presented at the Annual Meeting of the American Association of Neuromuscular and Electrodiagnostic Medicine, New Orleans, LA, September 15, 2016.
181. Cortical plasticity in dystonia. Presented at Summit on dystonia: Targeting neural circuitries in dystonia, the 8th Tyler’s Hope Annual Think Tank, College of Medicine, University of Florida, Gainesville, FL, September 16, 2016.
182. Neural plasticity in Parkinson’s disease. Presented at the 2nd International Forum on Motor Control and Parkinson’s Disease, Beijing, China, September 26, 2016.
183. Voluntary movements construct summary. Presented at National Institute of Mental Health Motor Domain Workshop, Bethesda, MD, November 3, 2016.
184. Cortical plasticity with subthalamic nucleus stimulation in Parkinson’s disease. Presented at 2016 E. Harry Botterell Lectureship in Neurosurgery, Toronto, ON, November 11, 2016.
185. Overview of transcranial magnetic stimulation and TMS technology. Presented at Introduction to Administering rTMS for Physicians, Temerty Centre for Therapeutic Brain Intervention, Toronto, Ontario, November 25, 2016
186. Clinical applications of TMS: Stroke, Parkinson’s Disease and other Movement Disorders. Presented at Introduction to Administering rTMS for Physicians, Temerty Centre for Therapeutic Brain Intervention, Toronto, Ontario, November 25, 2016
187. Botulinum toxin for movement disorders. Presented at the meeting of the Hong Kong Movement Disorders Society Seminar, Hong Kong, China, February 20, 2017
188. Transcranial Magnetic in Parkinson’s Disease. Presented at Research Seminar, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China, February 20, 2017
189. Chemodenervation in movement disorders: Applications in Parkinsonsim. Presented at the 1st Pan American Parkinson’s Disease and Movement Disorders Congress, Miami, FL, February 25, 2017.
190. Methods to examine I-wave interactions and effects of afferent input. Presented at the 2nd International Brain Stimulation Conference, Barcelona, Spain, March 8, 2017.
191. Noninvasive Stimulation in Movement Disorders. Presented at the 21st International Congress of Parkinson’s Disease and Movement Disorders, Vancouver, June 6, 2017.
192. Basal ganglia oscillations and basal‐ganglia cortical interactions. Presented at Eppendorfer Neurologisches Kolloquium, Hamburg, Germany, June 28, 2017.
193. Subthalamic and internal globus stimulation: Effects on cortical plasticity. Presented at 16th European Congress of Clinical Neurophysiology, Budapest, Hungary, August 31, 2017.
194. Deep brain stimulation in movement disorders. Presented at the XXIII World Congress of Neurology, Kyoto, Japan, September 20, 2017.
195. Evaluation of cortical plasticity after human hand transplantation. Presented at 16th Annual Ralph T. Manktelow Lectureship in Hand Surgery program, Toronto, Ontario, October 20, 2017.
196. How is brain plasticity related to Parkinson’s disease and dystonia? Presented at Movement Disorders Speakers Series, Toronto, Ontario, October 25, 2017.
197. Lower limb anatomy. Presented at Canadian Botulinum Toxin Conference 2017, Toronto, Ontario, October 28, 2017.
198. Overview of TMS and rTMS technology. Presented at Repetitive Transcranial Magnetic Stimulation in Psychiatry Course, Temerty Centre for Therapeutic Brain Intervention, Toronto, Ontario, November 9, 2017.
199. rTMS in stroke, Parkinson’s disease and other movement disorders. Presented at Repetitive Transcranial Magnetic Stimulation in Psychiatry Course, Temerty Centre for Therapeutic Brain Intervention, Toronto, Ontario, November 9, 2017.
200. Transcranial magnetic stimulation in Parkinson’s disease. Presented at 2nd Annual Conference on Neurodegenerative Disease of Chinese Neuroscience Society, the 2nd Annual Conference on Geriatric Neurology of Geriatric Medicine Branch, China Gerontological Society, and 2018 Shanghai Ruijin International Forum of Neurodegenerative disease, Shanghai, China, March 10, 2018.
201. Beyond basal ganglia: Effects of deep brain stimulation on cortical activity. Presented at 31st International Congress of Clinical Neurophysiology, Washington DC, USA, May 5, 2018.
202. Transcranial magnetic stimulation to measure the effects of deep brain stimulation on cortical activities. Presented at the 95th Annual Conference of the American Congress of Rehabilitation Medicine, Dallas TX, USA, September 30, 2018.
203. Basal ganglia function and basal ganglia-cortical relationships: Insights from basal ganglia recordings and stimulation. Presented at the First China Parkinson Alliance Conference and the Third International Forum on Motor Control and Parkinson’s Disease, Beijing, China, October 11, 2018.
204. Safety of transcranial magnetic stimulation in combination with metal and electrode brain implants. Presented at transcranial magnetic stimulation meeting: Safety and Ethical Guidelines, Siena, Italy, October 18, 2018.
205. Neurophysiology for diagnosis of movement disorders. Presented at the meeting of the Hong Kong Movement Disorders Society, Hong Kong, November 12, 2018.
206. Basal ganglia functions and cortical plasticity. Presented at Research Seminar, Department of Kinesiology, McMaster University, Hamilton, Ontario, February 14, 2019.
207. Basal ganglia functions and basal-ganglia cortical connections. Presented at Hospital for Sick Children Neuroimaging Rounds, Toronto, Ontario, February 21, 2019
208. Electrophysiological assessment of movement disorders. Presented at Dystonia Expert Exchange, Toronto, Ontario, March 1, 2019
209. Cortical plasticity in Parkinson’s disease and dystonia. Presented at the 8th Inje University Paik Hospital Parkinson’s Disease Symposium, Seoul, Korea, April 18, 2019.
210. Electrophysiolgical assessment of movement disorders: Clinical and research applications. Presented at 2019 Korean Movement Disorders Society Spring Symposium, Seoul, Korea, April 20, 2019.
211. Transcranial magnetic stimulation as treatment for movement disorders: Present and
future perspectives. Presented at the 3rd International Taiwanese Congress of Neurology, Taipei, Taiwan, May 5, 2019.
212. Botulinum toxin therapy: Anatomical basis. Presented at the 4th International Congress on Treatment of Dystonia, Hannover, Germany, May 9, 2019.
213. Inhibitory functions of the basal ganglia and influence of basal ganglia on cortical plasticity. Presented at the 6th Annual Movement Disorders Retreat, London, Ontario, June 22, 2019.
214. Non-invasive brain stimulation as treatment for movement disorders. Presented at University of Manitoba Neurology Rounds, Winnipeg, Manitoba, August 29, 2019.
215. Role of electrophysiological studies in diagnosis of movement disorders. Presented at University of Manitoba Neurology Residents’ Rounds, Winnipeg, Manitoba, August 30, 2019.
216. Non-invasive brain stimulation as treatment for Parkinson’s disease. Presented at Canada-China Medical Seminar, Xiangtan City Hospital, China, October 17, 2019.
217. Transcranial magnetic stimulation as treatment for Parkinson’s disease: Present and
future perspectives. Presented at 7th Congress of Neuro-Degenerative Diseases Committee (NDDC) of the Chinese Society of Microcirculation and the 4th Beijing International Neuro-Degenerative Diseases Summit Symposium, Beijing, China, October 19, 2019.
218. Low-intensity focused ultrasound for neuromodulation. Presented at Neurology Faculty Research Day, University of Toronto, Toronto, Ontario, December 6, 2019.
STUDENT/POSTDUCTORAL SUPERVISION
Master’s Thesis [n=7]
Principal Supervisor James Saravanamuttu (Completed), University of Toronto Student Degree Start Date: 2016/9
Student Degree Received Date: 2019/7
Project Description: Interactions between cortical inhibition and facilitation in Parkinson’s disease
Present Position: Medical Student, University of Toronto
Principal Supervisor Anuj Rastogi (Completed), University of Toronto
Student Degree Start Date: 2013/9
Student Degree Received Date: 2016/6
Project Description: Effects of cerebellar stimulation on brain connections
Present Position: Medical Student, Royal College Surgeons in Ireland
Principal Supervisor Susy Lam (Completed), University of Toronto
Student Degree Start Date: 2013/9
Student Degree Received Date: 2015/8
Project Description: Parietal motor cortical interaction in sensorimotor adaptation
Present Position: Medical Student, University of Toronto
Principal Supervisor Nina Bahl (Completed), University of Toronto
Student Degree Start Date: 2009/9
Student Degree Received Date: 2012/12
Project Description: Induction of plasticity with magnetic stimulation and STN DBS
Present Position: Research Associate, Stanford University
Principal Supervisor Giannina Descalzi (Completed), University of Toronto
Student Degree Start Date: 2006/1
Student Degree Received Date: 2008/9
Project Description: Cortical plasticity following facial reconstruction.
Present Position: Postdoctoral fellow, New York University
Principal Supervisor Jason Chu (Completed), University of Toronto
Student Degree Start Date: 2004/9
Student Degree Received Date: 2006/8
Project Description: Interaction between inhibitory systems in the motor cortex
Present Position: Assistant Professor of Neurological Surgery, University of Southern California
Doctorate [n=12]
Principal Supervisor Stephanie Tran (In Progress), University of Toronto
Student Degree Start Date: 2018/9
Present Position: PhD
Principal Supervisor Cricia Rinchon (In Progress), University of Toronto
Student Degree Start Date: 2016/9
Present Position: PhD
Principal Supervisor Julianne Baarbe (In Progress), University of Toronto
Student Degree Start Date: 2015/9
Present Position: PhD
Principal Supervisor Ayda Ghahremani (Completed) , University of Toronto
Student Degree Start Date: 2013/9
Student Degree Received Date: 2017/6
Project Description: Role of the basal ganglia in stopping movements
Present Position: Postdoctoral Fellow, Stanford University
Principal Supervisor Gaayathiri Jegatheeswaran (Completed), University of Toronto
Student Degree Start Date: 2012/9
Student Degree Received Date: 2018/12
Project Description: Sensory disturbances in Parkinson’s disease
Present Position: Research Associate, Toronto Rehabilitation Institute
Co-Supervisor Takashi Yoshida (Completed), University of Toronto
Student Degree Start Date: 2011/9
Student Degree Received Date: 2018/8
Project Description: EEG studies of gait disturbance in Parkinson’s disease
Present Position: Postdoctoral Researcher, University of Gottingen, Germany
Principal Supervisor Philippe Huot (Completed), University of Toronto
Student Degree Start Date: 2008/7
Student Degree Received Date: 2011/12
Project Description: The serotonergic system in Parkinson’s disease
Present Position: Assistant Professor, McGill University
Principal Supervisor Elahi Behzad (Completed), University of Toronto
Student Degree Start Date: 2008/1
Student Degree Received Date: 2012/12
Project Description: Motor learning and associative plasticity
Present Position: Clinical Fellow, Mayo Clinic
Principal Supervisor Eric Tsang (Completed), University of Toronto
Student Degree Start Date: 2006/9
Student Degree Received Date: 2012/4
Project Description: Basal ganglia oscillations in Parkinson’s disease and dystonia.
Present Position: Assistant Professor, Hong Kong Polytechnic University
Principal Supervisor Molnar Greg (Completed), University of Toronto
Student Degree Start Date: 2000/9
Student Degree Received Date: 2005/9
Project Description: Mechanisms of thalamic deep brain stimulation
Present Position: Director, Neuromodulation Research, University of Minnesota
Principal Supervisor Cunic Danny (Completed), University of Toronto
Student Degree Start Date: 2000/9
Student Degree Received Date: 2004/12
Project Description: Functional assessment of the subthalamic nucleus
Present Position: Physician
Co-Supervisor Z. Jeffrey Daskalakis (Completed), University of Toronto
Student Degree Start Date: 1999/9
Student Degree Received Date: 2002/9
Project Description: Cortical inhibition in schizophrenia
Present Position: Professor of Psychiatry, University of Toronto
Post-doctorate [n=43]
Principal Supervisor Ghazaleh Darmani (In Progress), University of Toronto
Start Date: 2019/9
Present Position: Post-Doctoral Fellow
Principal Supervisor Yeow Hoay Koh (Completed), University of Toronto
Start Date: 2019/6
Completion Date: 2019/12
Present Position: Clinical lecturer, National University of Singapore
Principal Supervisor Jieun Lee (Completed), University of Toronto
Start Date: 2019/3
Completion Date: 2019/8
Present Position: Clinical Assistant Professor, Department of Neurology, National Health Insurance Service Ilsan Hospital, Seoul, Korea
Principal Supervisor Jean-Francois Nankoo (In Progress), Krembil Brain Institute
Start Date: 2018/9
Present Position: Post-Doctoral Fellow
Principal Supervisor Stanley Chen (Completed), University of Toronto
Start Date: 2018/7
Completion Date: 2019/6
Present Position: Head, Department of Neurology, National Taiwan University Hospital
Principal Supervisor Roaa Khallaf (Completed), University of Toronto
Start Date: 2018/7
Completion Date: 2019/6
Present Position: Attending Neurologist, Saudi Arabia
Principal Supervisor Ke Zeng (In Progress), Krembil Research Institute
Start Date: 2018/2
Present Position: Post-Doctoral Fellow
Principal Supervisor Neil Drummond (In Progress), Krembil Research Institute
Start Date: 2017/9
Present Position: Post-Doctoral Fellow
Principal Supervisor Ji-Young Kim, Krembil Research Institute
Start Date: 2017/2
Completion Date: 2018/1
Present Position: Associate Professor, Inje University, Korea
Principal Supervisor Karine Garneau (Completed), University of Toronto
Start Date: 2017/7
Completion Date: 2017/12
Present Position: Assistant Professor, University of Montreal
Principal Supervisor Harneet Singh (Completed), University of Toronto
Start Date: 2016/7
Completion Date: 2017/6
Present Position: Neurologist, Toronto
Principal Supervisor Anne Weissbach (Completed), University of Toronto
Start Date: 2016/7
Completion Date: 2017/4
Present Position: Neurology resident, University of Lubeck, Germany
Principal Supervisor Matt Brown (Completed), Krembil Research Institute
Start Date: 2015/6
Completion Date: 2017/8
Present Position: Assistant Professor, Department of Kinesiology and Health Science California State University
Principal Supervisor Natasha Radhu (Completed), Krembil Research Institute
Start Date: 2015/11
Completion Date: 2016/8
Present Position: Medical Science Liaison, Novartis Canada
Principal Supervisor Ghada Mousa (Completed), University of Toronto
Start Date: 2014/8
Completion Date: 2015/7
Present Position: MD
Principal Supervisor Reina Isayama (Completed), University of Toronto
Start Date: 2012/7
Completion Date: 2017/6
Project Description: Sensorimotor intergration in PD and dystonia
Present Position: Neurologist, Tokyo, Japan
Principal Supervisor Michael Vesia (Completed), Krembil Research Institute
Start Date: 2012/7
Completion Date: 2017/8
Project Description: Sensorimotor training in dystonia and PD
Present Position: Assistant Professor, Movement Science, School of Kinesiology, University of Michigan
Principal Supervisor Robin Cash (Completed), Krembil Research Institute
Start Date: 2011/12
Completion Date: 2017/2
Project Description: Interaction between cortical circuits
Present Position: Post-Doctoral Fellow, Monash University, Australia
Principal Supervisor Elisabeth Stiksrud (Completed), University of Toronto
Start Date: 2012/7
Completion Date: 2013/6
Project Description: Modulation of cognitive function in Parkinson’s disease with
transcranial direct current stimulation (tDCS)
Present Position: Neurology Resident, University of Gottingen, Germany
Principal Supervisor Louise-Laure Mariani (Completed), University of Toronto
Start Date: 2012/4
Completion Date: 2012/12
Project Description: Premotor to motor cortex connectivity in Parkinson’s disease
Present Position: Assistant Professor, Hôpital Universitaire Pitié Salpêtrière, INSERM, Paris France
Principal Supervisor Wing Lok Au (Completed), University of Toronto
Start Date: 2012/4
Completion Date: 2012/10
Project Description: Neurophysiology of Movement Disorders
Present Position: Associate Professor, Duke-NUS Graduate Medical School Singapore; Head, Department of Neurology, National Neuroscience Institute, Singapore
Principal Supervisor Nicolas Phielipp (Completed), University of Toronto
Start Date: 2010/7
Completion Date: 2013/6
Project Description: Repetitive magnetic stimulation in Parkinson’s disease
Present Position: Assistant Professor of Neurology, UC Irvine, USA
Principal Supervisor Akihiro Yugeta (Completed) , University of Toronto
Start Date: 2010/4
Completion Date: 2012/11
Project Description: Influence of eye movements on basal ganglia activities
Present Position: Assistant Professor, University of Tokyo
Principal Supervisor Soumya Ghosh (Completed), University of Toronto
Start Date: 2010/2
Completion Date: 2011/6
Project Description: Interactions between cortical and interhemispheric inhibitions
Present Position: Clinical Associate Professor, University of Western Australia
Principal Supervisor Bogdan Neagu (Completed), Toronto Western Research Institute
Start Date: 2009/1
Completion Date: 2013/8
Project Description: Interactions between PPN and basal ganglia.
Present Position: Clinical Specialist, Conavi, Canada
Principal Supervisor Thomas Steeves (Completed), University of Toronto
Start Date: 2009/1
Completion Date: 2019/9
Project Description: Neurophysiology of Movement Disorders
Present Position: Assistant Professor, University of Toronto
Principal Supervisor Sang Jin Kim (Completed), University of Toronto
Start Date: 2008/5
Completion Date: 2009/10
Project Description: Effect of STN stimulation on cortical plasticity
Present Position: Associate Professor, Inje University, Korea
Principal Supervisor I-Jin Yeh (Completed), University of Toronto
Start Date: 2007/9
Completion Date: 2009/9
Project Description: Cortical evoked potentials from GPi stimulation
Present Position: Neurologist, Taiwan
Principal Supervisor Kaviraja Udupa (Completed), University of Toronto
Start Date: 2007/9
Completion Date: 2015/6
Project Description: Brain plasticity in dystonia
Present Position: Additional Professor, National Institute of Mental Health & Neuroscience, India
Principal Supervisor Renju Kuriakose (Completed), University of Toronto
Start Date: 2007/7
Completion Date: 2008/6
Project Description: Effects of subthalamic nucleus stimulation on cortical excitability
Present Position: Assistant Professor, Dalhousie University
Principal Supervisor Castillo Gabriel (Completed), University of Toronto
Start Date: 2007/7
Completion Date: 2008/6
Project Description: Effects of preomotor cortex stimulation in PD
Present Position: Neurologist, Columbia
Principal Supervisor Zhen Ni (Completed), Toronto Western Research Institute
Start Date: 2006/9
Completion Date: 2015/9
Project Description: Mechanisms of cortical inhibition and facilitation Present Position: Postdoctoral Fellow, NIH
Principal Supervisor Aimee Nelson (Completed), Toronto Western Research Institute
Start Date: 2005/9
Completion Date: 2008/1
Project Description: Somatosensory processing in dystonia
Present Position: Associate Professor & Canada Research Chair, McMaster University
Co-Supervisor Adam Kirton (Completed), University of Toronto
Start Date: 2005/7
Completion Date: 2007/6
Project Description: Magnetic stimulation as treatment in pediatric stroke
Present Position: Professor, Department of Pediatrics, University of Alberta
Principal Supervisor Pooya Pakarian (Completed), University of Toronto
Start Date: 2005/7
Completion Date: 2007/6
Project Description: Role of basal ganglia in voluntary movement
Present Position: Scientist, Iran
Principal Supervisor Michael Angel (Completed), University of Toronto
Start Date: 2005/7
Completion Date: 2006/7
Project Description: Physiology of spinal reflex circuits
Present Position: Lecturer, University of Toronto
Principal Supervisor Francesca Morgante (Completed), University of Toronto
Start Date: 2004/3
Completion Date: 2005/8
Project Description: Motor plasticity in Parkinson’s Disease
Present Position: Reader in Neurology, St. George’s, University of London
Principal Supervisor Aparna Wagle-Shukla (Completed), University of Toronto
Start Date: 2004/2
Completion Date: 2006/6
Project Description: STN stimulation and sensorimotor integration
Present Position: Assistant Professor, University of Florida
Principal Supervisor Alberto Espay (Completed), University of Toronto
Start Date: 2003/7
Completion Date: 2005/6
Project Description: Physiology of psychogenic dystonia
Present Position: Professor and endowed chair, University of Cincinnati
Principal Supervisor Ritsuko Hanajima (Completed), University of Toronto
Start Date: 2002/7
Completion Date: 2004/12
Project Description: SEPs from deep brain structures
Present Position: Professor of Neurology, Kitasato University, Japan.
Principal Supervisor Ji-Yuan Li (Completed), University of Toronto
Start Date: 2002/7
Completion Date: 2003/6
Project Description: Mechanisms of mirror movement in Parkinson’s Disease
Present Position: Assistant Professor, Kaohsiung, Taiwan
Principal Supervisor Pramod Kumar Pal (Completed), University of Toronto
Start Date: 2002/7
Completion Date: 2003/6
Project Description: Physiology of corticobasal degeneration
Present Position: Professor and Head, National Institute of Mental Health and Neuroscience, India
Principal Supervisor Sailer Alexandra (Completed), University of Toronto
Start Date: 2001/5
Completion Date: 2002/4
Project Description: Sensory input and cortical inhibition
Present Position: Physician, Umea University, Sweden
Principal Supervisor Paradiso Guillermo (Completed), Toronto Western Research Institute
Start Date: 1999/9
Completion Date: 2004/8
Project Description: Role of basal ganglia in voluntary movement
Present Position: Assistant Professor, Dalhousie University
Co-Supervisor Terence D. Sanger (Completed), University of Toronto
Start Date: 1999/7
Completion Date: 2000/6
Project Description: Mechanisms of intracortical inhibition
Present Position: Associate Professor, Keck School of Medicine, University of Southern California
OTHER PROFESSIONAL ACTIVITIES
Editor-in-Chief, Canadian Journal of Neurological Sciences (2013-present)
Journal Editorial Board Membership
Neurology (2010-present)
Frontiers in Neuroscience (2012-present)(Reviewing editor)
PLOSOne (2012-present)(Academic Editor)
Journal of Motor Behavior (2008–present)
Clinical Neurophysiology (2003-2009; 2011-2017)
Neural Plasticity (2009-2013)(Reviewing editor)
Canadian Journal of Neurological Sciences (2008-2013)
Muscle and Nerve (2006-2012)
Neurorehabilitation and Neural Repair (2005-2007)
Movement Disorders (2002-2005)
Peer-Reviewer for the Following Journals: Neurology, Movement Disorders, Canadian Journal of Neurological Sciences, Muscle and Nerve, Annals of Neurology, Experimental Brain Research, Clinical Neurophysiology, Journal of Neurophysiology, Experimental Neurology; Journal of Physiology, Brain, European Journal of Neuroscience, Journal of Neuroscience, Brain Research, Journal of Neurology, Neurosurgery and Psychiatry, Trends in Neuroscience, Neuroimage, Neurorehabilitation and Neural Repair, Journal of Motor Behavior, Current Biology, Lancet Neurology, Pain, Archives of Neurology, Nature Clinical Practice Neurology, Neurobiology of Aging, Brain Stimulation, Journal of Applied Physiology, Neurosignals, Parkinsonism and Related Disorders
Scientific Advisory Board
Parkinson Canada (2017-present)
Banting Research Foundation (2013-2015, 2017-2018)
Medical and Scientific Advisory Council, Dystonia Medical Research Foundation (2004-2007; 2010-2013)
Tourette Syndrome Association (2009-2015)
Michael Smith Foundation for Health Research (2007)
National Parkinson Foundation (2006)
External Reviewer for Granting Agencies
Wellcome Trust (2019, 2020)
Cleveland Clinic, Scientist Review (2019)
Canadian Institutes of Health Research (2002-present)
National Institutes of Health (2003, 2006, 2008, 2009, 2012, 2014, 2015, 2016, 2018)
German Research Foundation, DFG (2018)
Austrian Science Fund (2017)
Research Grant Council of Hong Kong (2017-9)
Collaborative Center X-linked Dystonia-Parkinsonism (2016)
St Michael’s Hospital, Scientist Review (2011)
Medical Research Council, UK (2010, 2019),
National Health and Medical Research Council of Australia (2009)
Health Sciences Foundation, Winnipeg (2009)
Parkinson Disease Association, UK (2009)
Michael J. Fox for Parkinson Research (2008, 2011)
Physician Services Incorporated Foundation (2008)
Oregon Center for Aging & Technology, National Institute of Aging Roybal Center (2008)
The American Institute of Biological Sciences (2006, 2007)
Rothman Research Institute, Scientist review (2006, 2008, 2011)
TV3 Marato Foundation, Spain (2006)
U.S.-Israel Binational Science Foundation (2006)
The Human Frontier Science Program (2006)
Tourette Syndrome Foundation (2006)
Canada Foundation for Innovation (2005),
National Science and Engineering Research Council of Canada (2005, 2007, 2008, 2009, 2018)
Michael Smith Foundation for Health Research (2004, 2019)
Alberta Heritage Foundation for Medical Research (2002-2003, 2009)
Swiss National Science Foundation (2002)
Austrian Science Council (2001)
University and Hospital Educational and Administrative positions
Interim Associate Dean, Physician Scientist Training, University of Toronto (12/2017-6/2018)
Acting Associate Dean, Physician Scientist Training, University of Toronto (10/2014-3/2015)
Member, Clinician Scientist Training Program, Department of Medicine, University of Toronto (2000 – present)
Associate Director, Clinician-Scientist Training Program, Department of Medicine, University of Toronto (2003 – 2006)
Director, Clinician-Scientist Training Program, Department of Medicine, University of Toronto (2006 – present)
Member, Clinician Investigator Program Committee, University of Toronto (2006 – present)
Member, Faculty of Medicine Research Committee, University of Toronto (2009- 2011)
Member, Faculty of Medicine Awards Committee, University of Toronto (2014 – present)
Member, Executive Committee, Department of Medicine, University of Toronto (2011- present)
Member, Core Internal Medicine Training Program Committee, Department of Medicine, University of Toronto (2003 – 2006)
Member, Research Committee, Department of Medicine, University of Toronto (2004 – present)
Chair, Research Committee, Division of Neurology, University of Toronto (2000 – 2017)
Member, Executive Committee, Division of Neurology, University of Toronto (2000 – 2017)
Member, Space Committee, Toronto Western Research Institute (2008 – 2015)
Member, Appointments Committee, Institute of Medical Science, University of Toronto (2012 – 2014)
Member, Banting Grants Review Committee, University of Toronto (2012- 2015, 2017)
Interim Executive Committee, Dystonia Study Group (2000 – 2002)
Member, Dystonia Study Group (2000 – present)
Member, Parkinson Study Group (2003 – present)
Lectures to General Public and Patient Groups
- Parkinson’s disease and Alzheimer’s disease. Presented at the Meeting of the Association of Professional Language Interpreters (APLI). December 5, 2019
- Modern Management of Parkinson’s disease. Presented at Heart and Brain Symposium, Chinese Canadian Heart and Brain Association, April 27, 2019
- Fairchild Chinese Radiothon, Radio Interview, March 7, 2019
- Fairchild Chinese Radiothon, Radio Interview, March 8, 2018
- Fairchild Radio, Sunday Health Expert Program, February 18, 2018
- Dystonia: Clinical Features, Diagnosis, Management and Research. Presented at Dystonia Information Session, Dystonia Medical Research Foundation of Canada, November 26, 2017
- How is brain plasticity related to Parkinson’s disease and dystonia, presented at Movement Disorders Speakers Series, Krembil Research Institute, University Health Network, Toronto, Ontario, October 25, 2017
- Parkinson’s disease, presented at Toronto Western Hospital, University Health Network, Toronto, Ontario, August 10, 2017 (in Chinese)
- Fairchild Chinese Radiothon, Radio Interview, March 26, 2015
- Parkinson’s disease, presented at Toronto Western Hospital, University Health Network, Toronto, Ontario, July 9, 2014 (in Chinese)
- Fairchild Chinese Radiothon, Radio Interview, March 6, 2014
- Globe and Mail article on Dystonia, November 20, 2011
- Fairchild Chinese Radiothon, Radio Interview, March 3, 2011
- Fairchild Chinese Radiothon, Radio Interview, March 9, 2010
- Talk show on CNKX Radio on Dystonia, November 7, 2008
- Discussion Panel Chair, screening of documentary “Twisted” organized by Dystonia Medical Research Foundation of Canada, Ontario Science Centre, October 16, 2008
- Discussion on Parkinson’s disease, in “Leisure Talk”, Fairchild Television, April 3 and 4, 2007 (in Chinese)
- Parkinson’s disease, presented at Toronto Western Hospital, University Health Network, Toronto, Ontario, January 26, 2007
- Parkinson’s disease, presented at Toronto Western Hospital, University Health Network, Toronto, Ontario, November 10, 2006 (in Chinese)